The Peptide CommonsEst. May 2024
Independent. We sell nothing and are affiliated with no manufacturer or pharmacy. Every moderation action is logged in public
Intersection · Clinical × obstructive sleep apnoea

Clinical topics tagged obstructive sleep apnoea

Topics in Clinical carrying the tag obstructive sleep apnoea. A comorbidity with its own trial evidence in this class.

20 topics

TopicParticipantsRepliesViewsActivity
Osteoarthritis and mechanical versus metabolic improvement
Osteoarthritis and mechanical versus metabolic improvement Writing it up because I had to work it out twice and would rather nobody else did. Asking about osteoarthritis and mechanical versus metabolic…
NANRFKLWDP+2 6 30k 12h
Type 2 diabetes and the largest part of the evidence base — does this still hold?
Type 2 diabetes and the largest part of the evidence base — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Trying to work out what would count…
EAASVBSDFW+17 22 4.5k 1d
PCOS and metabolic overlap: what is and is not studied
On the subject in the title: PCOS and metabolic overlap: what is and is not studied Working notes rather than a conclusion. PCOS and metabolic overlap, from the point of view of someone who has read the…
SGPGBST 3 6.6k 1d
Revisiting: PCOS and metabolic overlap: what is and is not studied
Revisiting: PCOS and metabolic overlap: what is and is not studied — setting out what I have, and where I think it stops being reliable. Trying to establish the boundary conditions on PCOS and metabolic…
FEMHRSOBKD+55 59 26k 2d
Heart failure with preserved ejection fraction: symptom endpoints
Heart failure with preserved ejection fraction: symptom endpoints — setting out what I have, and where I think it stops being reliable. Heart failure with preserved ejection keeps being re-asked here and I…
ITSGSRFVII+19 23 311 12d
Osteoarthritis and mechanical versus metabolic improvement — one year on
On the subject in the title: Osteoarthritis and mechanical versus metabolic improvement — one year on Working notes rather than a conclusion. Collecting what is known about Osteoarthritis and mechanical…
DVCCNKCOPO+52 56 8.1k 15d
Gastro-oesophageal reflux: improving or worsening?
The question in the title: Gastro-oesophageal reflux: improving or worsening? I will give what I have already checked below so nobody repeats it. Collecting what is known about gastro-oesophageal reflux in…
PMMNZDID+54 58 8.2k 1mo
Type 2 diabetes and the largest part of the evidence base
Posting this under the heading it deserves: Type 2 diabetes and the largest part of the evidence base Everything below is what sits behind that. Trying to work out what would count as evidence on type 2…
CNFNAISCJB+81 89 2.9k 3mo
Cardiovascular risk: reading the outcome trials as a set
Cardiovascular risk: reading the outcome trials as a set Writing it up because I had to work it out twice and would rather nobody else did. Reading back through what has been written here about cardiovascular…
JMVKEFHJKB 4 12k 5mo
Hepatic steatosis: what the MASH trial evidence supports — one year on
On the subject in the title: Hepatic steatosis: what the MASH trial evidence supports — one year on Working notes rather than a conclusion. Reading back through what has been written here about Hepatic…
VVSMG 2 4.1k 6mo
Revisiting: Gallbladder disease risk with rapid weight loss
Revisiting: Gallbladder disease risk with rapid weight loss Writing it up because I had to work it out twice and would rather nobody else did. Two things I would like separated before anyone answers on…
BVSLN 2 2k 9mo
[2026 update] Cardiovascular risk: reading the outcome trials as a set
Posting this under the heading it deserves: Cardiovascular risk: reading the outcome trials as a set Everything below is what sits behind that. I have spent a fortnight trying to pin Cardiovascular risk down…
SOAWKRLDNL+99 103 32k 11mo
Hepatic steatosis: what the MASH trial evidence supports
Hepatic steatosis: what the MASH trial evidence supports — setting out what I have, and where I think it stops being reliable. Trying to work out what would count as evidence on hepatic steatosis, before…
CMPCNLSMA+77 83 950 13mo
Obstructive sleep apnoea and a hard endpoint in this class
On the subject in the title: Obstructive sleep apnoea and a hard endpoint in this class Working notes rather than a conclusion. I was wrong about obstructive sleep apnoea in a thread last spring and I would…
OBFATWAKMS+120 129 1.8k 13mo
Second pass at: Obstructive sleep apnoea and a hard endpoint in this class
Second pass at: Obstructive sleep apnoea and a hard endpoint in this class — setting out what I have, and where I think it stops being reliable. Something about Obstructive sleep apnoea does not reconcile and…
SVCLRF 2 726 14mo
Revisiting: Heart failure with preserved ejection fraction: symptom endpoints
On the subject in the title: Revisiting: Heart failure with preserved ejection fraction: symptom endpoints Working notes rather than a conclusion. Working notes on Heart failure with preserved ejection rather…
SPDBOCASCN+4 8 43k 17mo
Gallbladder disease risk with rapid weight loss
Posting this under the heading it deserves: Gallbladder disease risk with rapid weight loss Everything below is what sits behind that. Gallbladder disease risk — I have the observation and I do not trust my…
IBRIJVPYR+56 63 34k 18mo
Hypertension improvement and when medication needs revisiting — a second dataset
Posting this under the heading it deserves: Hypertension improvement and when medication needs revisiting — a second dataset Everything below is what sits behind that. Posting a small dataset on Hypertension…
RMKBMMSCDT+126 133 22k 21mo
Type 2 diabetes and the largest part of the evidence base — does this still hold?
Type 2 diabetes and the largest part of the evidence base — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Trying to work out what would count…
NANKEML+18 25 1.7k 22mo
Chronic kidney disease and the FLOW result
Posting this under the heading it deserves: Chronic kidney disease and the FLOW result Everything below is what sits behind that. Chronic kidney disease: setting out the arithmetic in full, because I have had…
PAVOFJCN+34 38 33k 23mo