The Peptide CommonsEst. May 2024
Independent. We sell nothing and are affiliated with no manufacturer or pharmacy. Every moderation action is logged in public
Evidence · Preprints · continued

A preprint whose numbers changed substantially at publication posts 61–90

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

EF
endo_fellow_rkTL3Endocrinology fellow21 Sep 2025#61

Coming back to post #59, because the follow-up matters more than the original answer.

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

9 likes 10mo
YA
y.adebayoTL2 Moderator22 Sep 2025#62
FConsidine, post #28: Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently. Go to post

Picking up post #59: that is the part I would want checked first.

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

2 likes in reply to #28 10mo
MH
ms_hollowayTL4Mass spectrometrist22 Sep 2025#63

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

0 likes 10mo
MI
m.ibarraTL2 Moderator23 Sep 2025 · edited#64

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

21 likes 10mo
FN
formulary_notesTL3Regular24 Sep 2025#65

I read post #63 twice before replying, because I had assumed the opposite.

Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real.

14 likes 10mo
CA
c.amankwahTL2 Moderator25 Sep 2025#66
dr.villanueva, post #36: Worth separating two things that post #32 runs together. Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound. Go to post

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

5 likes in reply to #36 10mo
TH
TL4_HalvorsenTL4Leader · Journal club26 Sep 2025#67
methods_draft, post #22: This follows post #19 rather than contradicting it. What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint. Go to post

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

0 likes in reply to #22 10mo
RE
r.ekstromTL2 Moderator26 Sep 2025#68

post #67 is right about the mechanism and I think understates the practical bit.

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

29 likes 10mo
NM
n.moreauTL2 Moderator27 Sep 2025 · edited#69
k.pereira, post #60: Coming back to post #58, because the follow-up matters more than the original answer. Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound. Go to post

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

3 likes in reply to #60 10mo
PM
p.mbekiTL2 Moderator28 Sep 2025#70

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

0 likes 10mo
SO
sa.okonkwoTL2 Moderator29 Sep 2025#71

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

16 likes 10mo
AW
a.westergaardTL3Regular30 Sep 2025#72

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

31 likes 10mo
MM
m.malinowskiTL2 Moderator30 Sep 2025#73
n.petrov, post #18: Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim. Go to post

This follows post #70 rather than contradicting it.

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

1 like in reply to #18 10mo
ML
m.lindqvistTL2 Moderator1 Oct 2025#74
e.iyer, post #35: Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting. Go to post

I read post #72 twice before replying, because I had assumed the opposite.

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

6 likes in reply to #35 10mo
RR
r.restrepoTL2 Moderator2 Oct 2025 · edited#75

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

10 likes 10mo
CC
c.correiaTL2 Moderator3 Oct 2025#76

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

23 likes 10mo
ME
me.eriksenTL2 Moderator3 Oct 2025#77
e.bakken, post #27: Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim. Go to post

Picking up post #74: that is the part I would want checked first.

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

0 likes in reply to #27 10mo
KS
k.salinasTL2 Moderator4 Oct 2025#78
l.dziedzic, post #45: Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently. Go to post

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

3 likes in reply to #45 10mo
AM
a.molnarTL2 Moderator5 Oct 2025#79

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

6 likes 10mo
I
IbrahimoviTL2Member6 Oct 2025#80

Worth separating two things that post #76 runs together.

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

16 likes 10mo
BJ
b.jankowiakTL3Regular6 Oct 2025#81

Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real.

3 likes 10mo
JF
j.falkTL2 Moderator7 Oct 2025#82
e.almeida, post #51: Picking up post #48: that is the part I would want checked first. What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint. Go to post

post #81 is right about the mechanism and I think understates the practical bit.

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient.

0 likes in reply to #51 10mo
BE
bench_entryTL3Regular8 Oct 2025#83

I read post #81 twice before replying, because I had assumed the opposite.

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

32 likes 10mo
IW
i.wojcikTL2 Moderator9 Oct 2025#84

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

17 likes 10mo
ST
slow_titratorTL29 Oct 2025#85
NK
n.kravchenkoTL2 Moderator10 Oct 2025#86
y.adebayo, post #62: Picking up post #59: that is the part I would want checked first. Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently. Go to post

post #85 answers the question as asked. The question underneath it is different.

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

1 like in reply to #62 10mo
YM
y.mensahTL3Wiki editor11 Oct 2025#87

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

0 likes 10mo
HE
h.espinozaTL2 Moderator12 Oct 2025#88

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

23 likes 10mo
ED
e.dalgleishTL3Regular12 Oct 2025#89

Worth separating two things that post #85 runs together.

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

11 likes 10mo
SS
s.salgadoTL2 Moderator13 Oct 2025#90

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

3 likes 9mo