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Clinical · Comorbidities

Chronic kidney disease and the FLOW result — a second dataset

CT
c.tullochTL2 Moderator8 Oct 2024#1

Chronic kidney disease and the FLOW result — a second dataset Writing it up because I had to work it out twice and would rather nobody else did.

General question, not a request for advice about my own care — I know the difference and I would rather be told to see my prescriber than get an answer that pretends otherwise.

I have a panel in front of me with one value outside the reference interval and everything else within it. My instinct is that a single out-of-range result on a single draw is close to uninformative, and I would like to understand how the people who read these professionally think about that.

What I am actually asking is how to tell an interesting result from an uninteresting one before booking an appointment about it.

11 likes 22mo
MM
m.marchettiTL2 Moderator31 Oct 2024#2

the opening post is right about the mechanism and I think understates the practical bit.

PCOS and metabolic overlap: polycystic ovary syndrome has metabolic overlap with obesity and insulin resistance. Data on compounds in this class in PCOS specifically is thin; most discussion is by mechanism.

1 like 21mo
HH
h.hutchingsTL1Member16 Nov 2024#3
m.marchetti, post #2: the opening post is right about the mechanism and I think understates the practical bit. PCOS and metabolic overlap: polycystic ovary syndrome has metabolic overlap with obesity and insulin resistance. Data on compounds in this class in PCOS specifically is thin; most discussion is by mechanism. Go to post

Interactions between comorbidities: diabetes and kidney disease together change the risk calculation for hypoglycemia and for medication clearance. They are not independent variables.

30 likes in reply to #2 20mo

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