Practice · Administration

Leak-back after withdrawal and whether you lost a meaningful dose

Practice › Administration missed dose injection site reaction injection site rotation aseptic technique subcutaneous injection

st.dialloTL2 Moderator5 Jul 2026#1

Posting this under the heading it deserves: Leak-back after withdrawal and whether you lost a meaningful dose Everything below is what sits behind that.

Reporting something rather than asking about it, in case the pattern is useful to anyone else.

Over 26 weeks I logged this consistently: date, dose, time of day, and a simple severity score from 0 to 4 for each symptom. That is 118 data points, all self-reported, all unblinded, and collected by someone who knew what he expected to find. Treat it accordingly.

The reason I am posting is that my experience does not match the shape people usually describe here, and I would like to know whether that is unusual or whether the usual description is just the loudest version.

0 likes 23d

j.palaciosTL2 Moderator18 Jul 2026#2

Pinch or no pinch: the decision depends on needle length and on your own anatomy. A longer needle (8 mm and up) reaches subcutaneous tissue easily without a pinch. A shorter needle (4-6 mm) is safer with a gentle pinch. The pinch size matters less than people think; the injection angle matters more.

2 likes 10d

BDraganovTL2Member28 Jul 2026#3

st.diallo, post #1: Posting this under the heading it deserves: Leak-back after withdrawal and whether you lost a meaningful dose Everything below is what sits behind that. Reporting something rather than asking about it, in case the pattern is useful to anyone else. Over 26 weeks I logged this consistently: date, dose, time of day, and a simple severity… Go to post

Leak-back after withdrawal: a small amount of liquid on the skin after withdrawal is ordinary. Whether you lost a "meaningful" dose depends on concentration and your target dose, but some leak-back is universal and does not need to be treated as an error.

14 likes in reply to #1 3h

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