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Topic summary

Second pass at: Leak-back after withdrawal and whether you lost a meaningful dose

This is a generated summary. It shows the 5 most-liked posts from a topic of 23, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.
ZA
z.adeyemiTL2 Moderator10 Mar 2026#4

the opening post answers the question as asked. The question underneath it is different.

Pinch or no pinch: the decision depends on needle length and on your own anatomy. A longer needle (8 mm and up) reaches subcutaneous tissue easily without a pinch. A shorter needle (4-6 mm) is safer with a gentle pinch. The pinch size matters less than people think; the injection angle matters more.

28 likes 5mo
CV
ca.vermeulenTL2 Moderator8 Apr 2026#8
z.adeyemi, post #4: the opening post answers the question as asked. The question underneath it is different. Pinch or no pinch: the decision depends on needle length and on your own anatomy. A longer needle (8 mm and up) reaches subcutaneous tissue easily without a pinch. A shorter needle (4-6 mm) is safer with a gentle pinch. The pinch size matters less… Go to post

Injecting into an area that has become firm: lipohypertrophy — thickened fatty tissue from repeated injection in one area — changes local tissue absorption. Avoid injecting into areas that are noticeably firm or lumpy and allow those areas to recover for at least a few months.

21 likes in reply to #4 4mo
G
GEldridgeTL3Regular14 Apr 2026#9

Angle of injection: 90 degrees into pinched tissue ensures subcutaneous placement. It is not always necessary and shallower angles can work, but 90 degrees into a small pinch is the safest technique to learn first.

20 likes 3mo
IA
i.amankwahTL2 Moderator15 May 2026#14
z.adeyemi, post #4: the opening post answers the question as asked. The question underneath it is different. Pinch or no pinch: the decision depends on needle length and on your own anatomy. A longer needle (8 mm and up) reaches subcutaneous tissue easily without a pinch. A shorter needle (4-6 mm) is safer with a gentle pinch. The pinch size matters less… Go to post

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

26 likes in reply to #4 2mo
JP
j.petrovTL2 Moderator3 Jul 2026#23
m.ferrand, post #19: I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient. Go to post

Injecting into an area that has become firm: lipohypertrophy — thickened fatty tissue from repeated injection in one area — changes local tissue absorption. Avoid injecting into areas that are noticeably firm or lumpy and allow those areas to recover for at least a few months.

31 likes in reply to #19 25d

Read the full topic (23 posts)

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