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Intersection · Clinical × chronic kidney disease

Clinical topics tagged chronic kidney disease

Topics in Clinical carrying the tag chronic kidney disease. Renal outcomes and dose considerations.

35 topics

TopicParticipantsRepliesViewsActivity
Adolescents: a distinct evidence base
Adolescents: a distinct evidence base Writing it up because I had to work it out twice and would rather nobody else did. What changes if the standard account of adolescents is wrong? I ask because I have been…
RMAJGTIG 3 11k 9h
About the Comorbidities category
Type 2 diabetes, hepatic steatosis, sleep apnoea, cardiovascular and renal disease. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its author…
DOJMKHBMCE 4 16k 12h
Osteoarthritis and mechanical versus metabolic improvement
Osteoarthritis and mechanical versus metabolic improvement Writing it up because I had to work it out twice and would rather nobody else did. Asking about osteoarthritis and mechanical versus metabolic…
NANRFKLWDP+2 6 30k 12h
Type 2 diabetes and the largest part of the evidence base — does this still hold?
Type 2 diabetes and the largest part of the evidence base — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Trying to work out what would count…
EAASVBSDFW+17 22 4.5k 1d
Athletes in weight-category sports: a different risk calculus
Athletes in weight-category sports: a different risk calculus — setting out what I have, and where I think it stops being reliable. Something about athletes in weight-category sports does not reconcile and I…
OOBSMCBVB+38 42 6.6k 1d
PCOS and metabolic overlap: what is and is not studied
On the subject in the title: PCOS and metabolic overlap: what is and is not studied Working notes rather than a conclusion. PCOS and metabolic overlap, from the point of view of someone who has read the…
SGPGBST 3 6.6k 1d
Osteoarthritis and mechanical versus metabolic improvement — one year on
On the subject in the title: Osteoarthritis and mechanical versus metabolic improvement — one year on Working notes rather than a conclusion. Collecting what is known about Osteoarthritis and mechanical…
DVCCNKCOPO+52 56 8.1k 15d
Gastro-oesophageal reflux: improving or worsening?
The question in the title: Gastro-oesophageal reflux: improving or worsening? I will give what I have already checked below so nobody repeats it. Collecting what is known about gastro-oesophageal reflux in…
PMMNZDID+54 58 8.2k 1mo
Type 2 diabetes and the largest part of the evidence base
Posting this under the heading it deserves: Type 2 diabetes and the largest part of the evidence base Everything below is what sits behind that. Trying to work out what would count as evidence on type 2…
CNFNAISCJB+81 89 2.9k 3mo
Pregnancy and pregnancy planning: contraindication and washout
Posting this under the heading it deserves: Pregnancy and pregnancy planning: contraindication and washout Everything below is what sits behind that. Pregnancy and pregnancy planning: setting out the…
CIBPMNIDHC+111 122 2.4k 3mo
Adolescents: a distinct evidence base — one year on
Posting this under the heading it deserves: Adolescents: a distinct evidence base — one year on Everything below is what sits behind that. A methods question rather than a substantive one, about Adolescents.…
NIGHNCVEF+78 88 9.3k 3mo
Older adults, sarcopenia risk, and the trade-off nobody quantifies
Older adults, sarcopenia risk, and the trade-off nobody quantifies — setting out what I have, and where I think it stops being reliable. Older adults: setting out the arithmetic in full, because I have had to…
VJSATYAJR+103 109 12k 5mo
Cardiovascular risk: reading the outcome trials as a set
Cardiovascular risk: reading the outcome trials as a set Writing it up because I had to work it out twice and would rather nobody else did. Reading back through what has been written here about cardiovascular…
JMVKEFHJKB 4 12k 5mo
Second pass at: Pregnancy and pregnancy planning: contraindication and washout
Second pass at: Pregnancy and pregnancy planning: contraindication and washout Writing it up because I had to work it out twice and would rather nobody else did. Something about Pregnancy and pregnancy…
BTJCOHNT+111 127 1.6k 6mo
Hepatic steatosis: what the MASH trial evidence supports — one year on
On the subject in the title: Hepatic steatosis: what the MASH trial evidence supports — one year on Working notes rather than a conclusion. Reading back through what has been written here about Hepatic…
VVSMG 2 4.1k 6mo
Older adults, sarcopenia risk, and the trade-off nobody quantifies — the long version
Older adults, sarcopenia risk, and the trade-off nobody quantifies — the long version — setting out what I have, and where I think it stops being reliable. A narrow question about Older adults, deliberately…
BVDTMBUCRV+64 69 15k 7mo
History of disordered eating and why it changes the conversation
History of disordered eating and why it changes the conversation Writing it up because I had to work it out twice and would rather nobody else did. What changes if the standard account of history of…
LDONKPWTP+20 24 30k 8mo
Revisiting: Gallbladder disease risk with rapid weight loss
Revisiting: Gallbladder disease risk with rapid weight loss Writing it up because I had to work it out twice and would rather nobody else did. Two things I would like separated before anyone answers on…
BVSLN 2 2k 9mo
Hypertension improvement and when medication needs revisiting
Hypertension improvement and when medication needs revisiting Writing it up because I had to work it out twice and would rather nobody else did. Hypertension improvement: setting out the arithmetic in full,…
ZCIMNBPSO+74 79 1.1k 10mo
Hepatic impairment and the absence of data
Hepatic impairment and the absence of data — setting out what I have, and where I think it stops being reliable. I was wrong about hepatic impairment in a thread last spring and I would like to correct it…
MAMLDYAWCC+30 35 32k 10mo
Follow-up: History of disordered eating and why it changes the conversation
Posting this under the heading it deserves: History of disordered eating and why it changes the conversation Everything below is what sits behind that. What changes if the standard account of History of…
LWFDAIRMRN+75 81 23k 10mo
[2026 update] Cardiovascular risk: reading the outcome trials as a set
Posting this under the heading it deserves: Cardiovascular risk: reading the outcome trials as a set Everything below is what sits behind that. I have spent a fortnight trying to pin Cardiovascular risk down…
SOAWKRLDNL+99 103 32k 11mo
Older adults, sarcopenia risk, and the trade-off nobody quantifies — does this still hold?
Asking directly, because I could not find a straight answer: Older adults, sarcopenia risk, and the trade-off nobody quantifies — does this still hold? Older adults: setting out the arithmetic in full,…
EFBPWM 2 22k 11mo
Hepatic steatosis: what the MASH trial evidence supports
Hepatic steatosis: what the MASH trial evidence supports — setting out what I have, and where I think it stops being reliable. Trying to work out what would count as evidence on hepatic steatosis, before…
CMPCNLSMA+77 83 950 13mo
Obstructive sleep apnoea and a hard endpoint in this class
On the subject in the title: Obstructive sleep apnoea and a hard endpoint in this class Working notes rather than a conclusion. I was wrong about obstructive sleep apnoea in a thread last spring and I would…
OBFATWAKMS+120 129 1.8k 13mo
[2026 update] Gastro-oesophageal reflux: improving or worsening?
Asking directly, because I could not find a straight answer: Gastro-oesophageal reflux: improving or worsening? Gastro-oesophageal reflux — I have the observation and I do not trust my interpretation of it,…
EFFIMDN 3 782 13mo
Second pass at: Obstructive sleep apnoea and a hard endpoint in this class
Second pass at: Obstructive sleep apnoea and a hard endpoint in this class — setting out what I have, and where I think it stops being reliable. Something about Obstructive sleep apnoea does not reconcile and…
SVCLRF 2 726 14mo
Revisiting: Heart failure with preserved ejection fraction: symptom endpoints
On the subject in the title: Revisiting: Heart failure with preserved ejection fraction: symptom endpoints Working notes rather than a conclusion. Working notes on Heart failure with preserved ejection rather…
SPDBOCASCN+4 8 43k 17mo
Coming back to: Renal impairment: what the labelling says about dose
Renal impairment: what the labelling says about dose — setting out what I have, and where I think it stops being reliable. Renal impairment — I have the observation and I do not trust my interpretation of it,…
NGDBCTJROF+30 34 48k 18mo
Gallbladder disease risk with rapid weight loss
Posting this under the heading it deserves: Gallbladder disease risk with rapid weight loss Everything below is what sits behind that. Gallbladder disease risk — I have the observation and I do not trust my…
IBRIJVPYR+56 63 34k 18mo