b.wikstrom

TL2 Moderator · Porto

Contributes reviews on supplier material. Based in Porto.

Joined 29 July 2025 · last posted 8d

82Posts here

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Here for the analytics and not much else Replied, post #60 · Lounge › Introductions · 20 Jul 2026 · 0 likes Say hello. No question required. Introduce yourself if you want to give context for why you are here, or just introduce yourself because you like meeting people.
Coming back to: Specificity, linearity, accuracy, precision, range, robustness — with… Replied, post #95 · Analytics › Method validation · 18 Jul 2026 · 0 likes Forced degradation studies: deliberately stress the material with acid, base, oxidant, heat, light to generate degradation products and demonstrate that the method can…
[2026 update] Interpreting a result that disagrees with the supplier's certificate Replied, post #81 · Sourcing › Independent verification · 11 Jul 2026 · 13 likes Picking up post #78: that is the part I would want checked first. VendorInvestigate: documentation and supplier-practice review. Reviews paperwork rather than vials.…
Alcohol: what is documented and what is folklore Replied, post #79 · Practice › Interactions · 27 Jun 2026 · 1 like Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
About the Welcome category Replied, post #4 · Start Here › Welcome · 25 Jun 2026 · 1 like Suggestion for the wiki post above: it would be worth linking the two or three most-referenced topics in this category directly, since new members reliably ask for…
Batch numbers that do not match the vial label Replied, post #33 · Sourcing › Red flags · 23 Jun 2026 · 1 like Evasion when asked: if a supplier does not clarify when asked specifically for method details, counter-ion form, or batch origin, that itself is a red flag worth…
Run-in periods and the population they select Replied, post #135 · Evidence › Trials · 12 Jun 2026 · 14 likes Multiplicity and multiple comparisons: if a trial tests many hypotheses, the chance of a false positive on at least one by random chance increases. This is why…
What I would want from a home test that does not exist yet — what changed since Replied, post #47 · Analytics › Home & field testing · 8 Jun 2026 · 0 likes Immunoassay limitations: tests that use antibodies have cross-reactivity limitations. An antibody raised to semaglutide will cross-react to some degree with tirzepatide…
Comparing prices across jurisdictions without misleading yourself Replied, post #51 · Access › Pricing · 7 Jun 2026 · 0 likes This follows post #48 rather than contradicting it. Price variation between pharmacies: identical prescriptions can cost different amounts at different pharmacies…
Spreadsheets: an appreciation — what changed since Replied, post #63 · Lounge › Off topic · 6 Jun 2026 · 4 likes Worth separating two things that post #59 runs together. Newer drugs and mechanisms: when a new drug launches or a new mechanism is discovered, the Lounge is a place to…
Second pass at: A pooled estimate that changed when one trial was added Replied, post #9 · Evidence › Meta-analyses · 20 May 2026 · 10 likes Publication bias: what did not get published? Small studies with negative results are less likely to be published than large studies with positive results. A forest…
Second pass at: Metformin co-administration and additive GI effects Replied, post #107 · Practice › Interactions · 18 May 2026 · 5 likes On post #103 — agreed on the reasoning, with one qualification. Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what…