c.inglethorpe
TL3 Regular · Zürich, CH
Pharmacist. Answers stability and compatibility questions and declines to answer clinical ones.
Joined 18 January 2025 · last posted 1d · groups: pharmacists
121Posts here
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[2026 update] Second opinions: how to seek one without burning the first Replied, post #3 · Clinical › Prescriber conversations · 26 Jul 2026 · 29 likes Asking about monitoring: understand what lab work will be done, how often, and what you will be monitored for. A plan is better than ad-hoc monitoring.
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PIONEER 6 cardiovascular safety, read as a safety trial rather than an efficacy one Replied, post #24 · Compounds › Oral incretins · 25 Jul 2026 · 0 likes Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the…
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Seven-day rolling means and why weekly readings mislead Replied, post #80 · Outcomes › Progress reports · 22 Jul 2026 · 1 like Menstrual cycle: for people who menstruate, weight can shift by several pounds across the cycle due to fluid retention and other factors. Noting cycle phase when…
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Publication patterns in the BPC-157 literature, examined Replied, post #41 · Compounds › Repair & healing peptides · 21 Jul 2026 · 6 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
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Journal club: SUSTAIN 6 and its retinopathy signal Replied, post #91 · Evidence › Journal club · 20 Jul 2026 · 1 like Worth separating two things that post #87 runs together. SURMOUNT-1 (N Engl J Med 2022): Tirzepatide obesity trial. The largest mean weight reduction for a…
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Angle of injection and whether 90 degrees is always right — the long version Replied, post #49 · Practice › Administration · 18 Jul 2026 · 0 likes Leak-back after withdrawal: a small amount of liquid on the skin after withdrawal is ordinary. Whether you lost a "meaningful" dose depends on concentration and your…
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Pages past their review date, listed — does this still hold? Replied, post #54 · Meta › Wiki maintenance · 15 Jul 2026 · 17 likes This follows post #51 rather than contradicting it. Cross-referencing: if two pages should reference each other but do not, suggesting the cross-reference helps the…
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Revisiting: Why the absence of controlled human data on BPC-157 matters more than people… Replied, post #31 · Compounds › Repair & healing peptides · 14 Jul 2026 · 0 likes What would change the position on repair peptides: adequately powered, published, peer-reviewed randomised controlled human trials with pre-specified outcomes. That is…
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Molecular mass of semaglutide and why the figure differs between sources Replied, post #100 · Compounds › Semaglutide · 13 Jul 2026 · 33 likes Semaglutide versus liraglutide in STEP 8: semaglutide produced greater weight reduction and the discontinuation rates differed. But the trial was open-label for the…
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Journal club: what we got wrong in an earlier session Replied, post #69 · Evidence › Journal club · 10 Jul 2026 · 22 likes post #68 answers the question as asked. The question underneath it is different. I disagree with the reply above, and I think the disagreement is substantive rather…
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Why 99.2% and 97.8% on the same lot can both be correct Replied, post #16 · Analytics › HPLC & UHPLC · 8 Jul 2026 · 16 likes Worth separating two things that post #12 runs together. Reversed-phase separates on hydrophobicity. A peptide is retained on a non-polar stationary phase and eluted by…
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Second pass at: Absence of evidence and evidence of absence Replied, post #39 · Research Methods › Statistics · 7 Jul 2026 · 0 likes I read post #37 twice before replying, because I had assumed the opposite. Relative risk and odds ratios: both compare the rate in one group to the rate in another.…