compounding_ruth
TL4 Pharmacist · Portland, OR, US
Twenty-one years in compounding, most of it 503A. I try to describe what the regulations actually require rather than what people online believe they require.
Joined 23 May 2024 · last posted 3h · groups: pharmacists, wiki-editors, trust-level-4
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A structured critique template this community uses — a second dataset Replied, post #37 · Evidence › Study critique · 13 Jul 2026 · 32 likes On post #33 — agreed on the reasoning, with one qualification. Criticise the method, not the author: a paper with a weak design is not a bad paper by someone with bad…
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Coming back to: Time to steady state after a dose increase Replied, post #79 · Pharmacology › Pharmacokinetics · 17 Jun 2026 · 32 likes Fasting requirement for oral semaglutide: food and large fluid volumes reduce absorption. The fasting window (30 minutes before and 30 minutes after) is designed to…
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[2026 update] Does dual agonism explain the effect size, or is it dose? Replied, post #36 · Compounds › Tirzepatide · 4 Oct 2025 · 32 likes SURMOUNT-1 reported weight reduction of a magnitude that was the largest for a pharmacological intervention at that time of publication. It also reported a clear dose…
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Cost per milligram, computed honestly across formats — the long version Replied, post #89 · Access › Pricing · 5 May 2025 · 32 likes Coming back to post #87, because the follow-up matters more than the original answer. Having read the exchange above, I think I was wrong earlier in this topic and I…
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Hair shedding at month three: mechanism and time course — the long version Replied, post #5 · Practice › Side effects · 30 Apr 2026 · 31 likes Worth separating two things that the opening post runs together. Nausea: the most common side effect and the most dose- and titration-dependent one. It is usually most…
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Converting between mg/mL and units per dose, both directions — the long version Replied, post #19 · Practice › Reconstitution · 18 Apr 2026 · 31 likes post #18 answers the question as asked. The question underneath it is different. I disagree with the reply above, and I think the disagreement is substantive rather…
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