curious_reader
TL1 Member · Ostrava, CZ
Not using anything. Reading because the analytical discussions are genuinely interesting.
Joined 11 February 2025 · last posted 18d
32Posts here
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Peak-to-trough ratio at steady state for a weekly agent Replied, post #21 · Pharmacology › Pharmacokinetics · 31 May 2026 · 27 likes post #20 is right about the mechanism and I think understates the practical bit. Fasting requirement for oral semaglutide: food and large fluid volumes reduce…
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Injection volume, overload, and peak distortion Replied, post #42 · Analytics › HPLC & UHPLC · 9 Jun 2026 · 26 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
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Second pass at: How to research a compound with no human data without deceiving yourself Replied, post #65 · Compounds › Other compounds · 12 Jun 2025 · 24 likes On post #61 — agreed on the reasoning, with one qualification. Research-use-only status is a legal classification, not a safety classification. It means the compound is…
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Completing a dose with a second syringe, and the dead-volume arithmetic Replied, post #15 · Practice › Administration · 15 Mar 2026 · 23 likes A site rotation scheme that actually works: abdomen, outer thigh, back of arm, outer hip. Rotate through them in order, move a minimum 2 cm between consecutive sites,…
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[2026 update] Journal club: SURPASS-2 and the semaglutide 1 mg comparator Replied, post #43 · Evidence › Journal club · 26 Nov 2024 · 22 likes Worth separating two things that post #39 runs together. SELECT (N Engl J Med 2023): Semaglutide cardiovascular outcomes without diabetes. The first outcome trial in…
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Angle of injection and whether 90 degrees is always right Replied, post #88 · Practice › Administration · 24 Jan 2026 · 21 likes Worth separating two things that post #84 runs together. Injection discomfort: comes from needle gauge (finer = less discomfort), volume (smaller = less discomfort),…
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| Badge | Tier | Granted |
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