e.almeida
TL2 Member · Haarlem, NL
Based in the EU. Tracks what is available and funded locally, and dates every claim.
Joined 20 September 2024 · last posted 10d · groups: regional-eu
95Posts here
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What a good consultation looks like from the other side Replied, post #60 · Clinical › Prescriber conversations · 18 Jul 2026 · 0 likes Discussing side effects: be specific. "Nausea" is less useful than "I have nausea worst 24 to 36 hours after injection, severity 2 to 3 out of 4, stable over weeks".…
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Journal club: what we got wrong in an earlier session Replied, post #89 · Evidence › Journal club · 16 Jul 2026 · 9 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
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[2026 update] Does a peptide degrade silently, with no visual change? Replied, post #87 · Practice › Storage & stability · 13 Jul 2026 · 0 likes This follows post #84 rather than contradicting it. I want to gently push back on the reply above about storage extrapolation. The advice is sound and the confidence is…
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Official shortage notices and what they authorise Replied, post #120 · Access › Shortages · 21 Jun 2026 · 13 likes Shortage predictions: regulators and suppliers issue shortage alerts before they become acute. Checking the regulatory website for shortages gives you advance notice.
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Why cagrilintide alone is discussed so much less than in combination — does this still… Replied, post #11 · Compounds › Cagrilintide & amylin analogues · 19 Jun 2026 · 1 like Historical amylin analogues: pramlintide was the only long-acting amylin analogue licensed for some time and its poor adherence was a known limitation. A weekly…
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Naming conventions for research peptides and the confusion they cause Replied, post #17 · Compounds › Other compounds · 18 Jun 2026 · 1 like Melanocortin agonists: mechanism involves the melanocortin-4 receptor pathway that regulates appetite. The documented adverse profile includes blood pressure elevation…
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Revisiting: How this community labels and discusses unrefereed work Replied, post #3 · Evidence › Preprints · 17 Jun 2026 · 10 likes Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the…
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Coming back to: Specificity, linearity, accuracy, precision, range, robustness — with… Replied, post #50 · Analytics › Method validation · 11 Jun 2026 · 23 likes I read post #48 twice before replying, because I had assumed the opposite. Robustness: the method gives consistent results when minor parameters vary. Tested by…
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Second pass at: Metformin co-administration and additive GI effects Replied, post #121 · Practice › Interactions · 7 Jun 2026 · 0 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
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A certificate whose chromatogram axes do not match its stated method — one year on Replied, post #42 · Sourcing › Red flags · 4 Jun 2026 · 1 like Rapid supplier turnover: a supplier that changes corporate structure, domain name, or contact repeatedly in short time windows raises suspicion about stability and…
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Semaglutide and gastric emptying — the mechanism behind most of the side-effect profile Replied, post #43 · Compounds › Semaglutide · 29 May 2026 · 21 likes The SELECT trial changed the positioning because it was the first cardiovascular outcome trial in people without diabetes. That decoupled the cardiovascular argument…
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Coming back to: Solubility limits and what a cloudy solution is telling you Replied, post #25 · Pharmacology › Formulation chemistry · 23 May 2026 · 0 likes Container closure: the vial material, rubber closure, and sealing all affect permeability to water and oxygen. Glass is less permeable than plastic. Rubber quality…
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- Access notes: PolandReview due 9 May 2027