f.fontaine

TL2 Moderator · Curitiba

Contributes reviews on supplier material. Based in Curitiba.

Joined 2 June 2025 · last posted 8d

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Which categories are strict and which are relaxed, honestly Replied, post #32 · Start Here › Welcome · 20 Jul 2026 · 2 likes On the reading order question specifically: start with the how-to-ask materials in this category, then read the one to three subcategories where your main questions…
Insomnia at a dose step: reported experiences — the long version Replied, post #49 · Wellbeing › Sleep · 20 Jul 2026 · 2 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
Request: tag synonyms surfaced in search Replied, post #17 · Meta › Feature requests · 13 Jul 2026 · 2 likes Feature scope: some requests are for the site itself (search, filtering, navigation). Some are for the documentation (new topics, different formats). Scope helps…
Coming back to: Payment method and the leverage it gives you, ranked Replied, post #19 · Sourcing › Payments · 13 Jul 2026 · 0 likes Cryptocurrency for payment: offers less fraud protection than credit cards and is final like bank transfer. Advantage: no geographic restrictions and no intermediary…
Carryover and the ghost peak from last week's standard — what changed since Replied, post #81 · Analytics › HPLC & UHPLC · 28 Jun 2026 · 24 likes Before anything else: what was the gradient, and at what wavelength? Area percent at different wavelengths is not the same number even on the same sample because…
Second pass at: Absence of evidence and evidence of absence Replied, post #30 · Research Methods › Statistics · 25 Jun 2026 · 5 likes On post #26 — agreed on the reasoning, with one qualification. Relative risk and odds ratios: both compare the rate in one group to the rate in another. Relative risk…
Carryover and the ghost peak from last week's standard — what changed since Replied, post #64 · Analytics › HPLC & UHPLC · 23 Jun 2026 · 4 likes Detection wavelength: 214 nm detects the peptide bond and is relatively insensitive to composition. 280 nm detects aromatic residues and is strongly…
When a dose reduction is the correct response to a side effect Replied, post #32 · Practice › Dosing & titration · 23 Jun 2026 · 19 likes post #31 is right about the mechanism and I think understates the practical bit. Dose equivalence between different incretin analogues is a weak concept. The molecules…
Official shortage notices and what they authorise Replied, post #108 · Access › Shortages · 15 Jun 2026 · 17 likes Allocation and rationing: during severe shortages, suppliers might ration allocation to prescribers. Understanding rationing policies from your prescriber matters for…
Pancreatitis history and the risk calculus Replied, post #19 · Safety › Contraindications · 15 Jun 2026 · 1 like Coming back to post #17, because the follow-up matters more than the original answer. Practical note that does not fit anywhere else. Whatever you conclude from this…
Injection volume, overload, and peak distortion Replied, post #47 · Analytics › HPLC & UHPLC · 12 Jun 2026 · 0 likes Column chemistry and particle size: smaller particles (1.7 μm) give better resolution and higher efficiency than larger particles (3.5 μm or 5 μm), at the cost of…
Receptor desensitisation as a tolerance hypothesis, and its weak evidence Replied, post #14 · Pharmacology › Receptor biology · 9 Jun 2026 · 12 likes Worth separating two things that post #10 runs together. Pharmacological class effects: all GLP-1 agonists slow gastric emptying and suppress appetite. Those are class…