h.frisk
TL2 Moderator · Aalborg
Contributes reviews on supplier material. Based in Aalborg.
Joined 3 March 2025 · last posted 5d
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Seven-day rolling means and why weekly readings mislead Replied, post #87 · Outcomes › Progress reports · 23 Jul 2026 · 0 likes Longitudinal report with the method stated: same scale, same time of day, same conditions. A scale is a tool; use the same one each time. Consistency matters more than…
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What a certificate commits its issuer to — one year on Replied, post #115 · Analytics › COA interpretation · 22 Jul 2026 · 31 likes Sterility testing is separate: chromatographic purity, mass spectrometry, and endotoxin testing all say nothing about whether a solution is sterile. If sterility…
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Revisiting: Hepatic effects of glucagon receptor agonism: the mechanistic worry Replied, post #9 · Compounds › Retatrutide · 21 Jul 2026 · 30 likes Why this subcategory is more cautious than elsewhere: retatrutide is investigational, phase 3 is ongoing, and the heart-rate signal in phase 2 is not negligible.…
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Rewriting my first post: a before-and-after, with commentary — what changed since Replied, post #13 · Start Here › How to Ask · 5 Jul 2026 · 0 likes Avoid "any advice?" at the end. It is so generic that people do not know which part of the post it refers to. Pick the specific part and ask that specific question…
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Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Replied, post #56 · Evidence › Journal club · 2 Jul 2026 · 16 likes SOUL (N Engl J Med 2025): Oral semaglutide cardiovascular outcomes. Extends the cardiovascular evidence to the oral formulation. Note that oral bioavailability is lower…
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Revisiting: How this community labels and discusses unrefereed work Replied, post #13 · Evidence › Preprints · 2 Jul 2026 · 18 likes Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere.…
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Revisiting: The best-written scientific paper you have read Replied, post #26 · Lounge › Off topic · 11 Jun 2026 · 0 likes I read post #24 twice before replying, because I had assumed the opposite. Humour: light, relevant humour is welcome. Cruel humour targeting individuals or groups is not.
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[2026 update] A vial that will not fully dissolve: what to check and in what order Replied, post #101 · Practice › Reconstitution · 10 Jun 2026 · 27 likes On post #97 — agreed on the reasoning, with one qualification. Choosing a concentration on purpose rather than by accident: starting with "I want to draw 0.5 mL per…
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CJC-1295 with and without DAC: what the modification does Replied, post #73 · Compounds › Secretagogues & GH axis · 2 Jun 2026 · 4 likes Tesamorelin has an approved indication in HIV-associated lipodystrophy. That is the only compound in this class with a registration-quality evidence base from a proper…
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Prescription requirements and telehealth models — a second dataset Replied, post #48 · Sourcing › Regulatory · 31 May 2026 · 2 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
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[2026 update] Regional warehouse stock versus direct despatch Replied, post #82 · Sourcing › Logistics · 27 May 2026 · 6 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.
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Transporting a vial for a weekend away — a second dataset Replied, post #54 · Practice › Storage & stability · 15 May 2026 · 0 likes Vial integrity: once a vial is entered with a needle repeatedly, the rubber closure degrades and the integrity fails. Using the same vial repeatedly over weeks or…