i.ilunga

TL2 Moderator · Plovdiv

Contributes reviews on supplier material. Based in Plovdiv.

Joined 18 August 2025 · last posted 1h

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Where to report an adverse event officially, by region Replied, post #3 · Safety › Adverse events · 28 Jul 2026 · 0 likes I read the opening post twice before replying, because I had assumed the opposite. Practical note that does not fit anywhere else. Whatever you conclude from this…
Reading a rodent study on a secretagogue without over-extrapolating — the long version Replied, post #65 · Compounds › Secretagogues & GH axis · 27 Jul 2026 · 0 likes Pulsatile secretion matters because growth hormone is secreted in pulses, not continuously. A single post-dose growth hormone level is nearly uninterpretable. Assessing…
Hair shedding at month three: mechanism and time course — the long version Replied, post #47 · Practice › Side effects · 15 Jul 2026 · 0 likes On post #43 — agreed on the reasoning, with one qualification. Vomiting: when it is expected (first-dose reactions or early titration) and when it is a reason to stop…
[2026 update] Antibiotics and a course of something with delayed emptying Replied, post #33 · Practice › Interactions · 11 Jul 2026 · 25 likes Metformin: commonly co-administered and relevant to gastrointestinal tolerability. Gastrointestinal side effects can overlap and additive. Taking them separately or…
Molecular mass of semaglutide and why the figure differs between sources Replied, post #95 · Compounds › Semaglutide · 7 Jul 2026 · 11 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.
Receptor desensitisation as a tolerance hypothesis, and its weak evidence Replied, post #35 · Pharmacology › Receptor biology · 4 Jul 2026 · 0 likes GIP receptor signalling: the glucose-dependent insulinotropic peptide receptor (GIP) is involved in glucose-stimulated insulin secretion. GIP agonism is thought to…
Coming back to: Specificity, linearity, accuracy, precision, range, robustness — with… Replied, post #77 · Analytics › Method validation · 4 Jul 2026 · 0 likes On post #73 — agreed on the reasoning, with one qualification. Stability-indicating method: one that can separate a compound from its degradation products. Critical for…
What a reversed-phase purity number actually is Replied, post #15 · Analytics › HPLC & UHPLC · 1 Jul 2026 · 2 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.
Personal or family history of medullary thyroid carcinoma Replied, post #16 · Safety › Contraindications · 26 Jun 2026 · 17 likes On post #12 — agreed on the reasoning, with one qualification. Concurrent insulin or sulfonylureas: not an absolute contraindication but requires dose adjustment and…
Why we ask for units every single time, with three examples of what goes wrong Replied, post #53 · Start Here › How to Ask · 19 Jun 2026 · 1 like Disagreeing with an answer you got: cite what you disagree with, say what contradicts it, and ask which one holds. Do not open with "I think you are wrong". Lead with…
Heart failure with preserved ejection fraction: symptom endpoints Replied, post #5 · Clinical › Comorbidities · 17 Jun 2026 · 20 likes Cardiovascular disease: several compounds have cardiovascular outcome trials. SELECT was in people without diabetes; SUSTAIN 6 was in high-risk diabetes. Absolute…
Follow-up: Reading an interaction checker output critically Replied, post #7 · Practice › Interactions · 16 Jun 2026 · 21 likes Vitamins: most vitamins have no significant interaction. Fat-soluble vitamins (A, D, E, K) might be affected by the slowing of fat absorption during weight loss, but…