j.silva
TL2 Moderator · Tours
Contributes reviews on supplier material. Based in Tours.
Joined 14 February 2025 · last posted 10d
80Posts here
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101Days visited
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Pregnancy and pregnancy planning: contraindication and washout Replied, post #21 · Clinical › Special populations · 22 Jan 2026 · 33 likes Older adults: sarcopenia risk is higher, polypharmacy is common, and the clinical trials did not enroll many people over 75. Extrapolating to very old people is…
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The C-cell question: rodent findings and their human context — what changed since Replied, post #12 · Compounds › Semaglutide · 18 Aug 2024 · 31 likes The C-cell question: semaglutide triggered medullary thyroid carcinoma in rodent toxicology studies. A signal in rodents does not automatically appear in humans, but it…
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Second pass at: How to research a compound with no human data without deceiving yourself Replied, post #24 · Compounds › Other compounds · 21 Feb 2025 · 30 likes Reading a supplier's product description as a marketing document: that is exactly what it is. The hyperbole, the mechanism written as fact, the theoretical benefits…
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A 5 mg vial and a 0.25 mg dose: the arithmetic in full — the long version Replied, post #8 · Practice › Reconstitution · 5 Jan 2025 · 30 likes Arithmetic step by step: a 5 mg vial with 2 mL of diluent gives (5 mg) / (2 mL) = 2.5 mg/mL. On a U-100 syringe at that concentration, 100 units = 1 mL = 2.5 mg, so…
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Packaging that arrived damaged: documenting it properly — a second dataset Replied, post #12 · Sourcing › Logistics · 25 Dec 2025 · 27 likes Insurance and carrier liability: most parcel carriers limit liability. Understanding the limits before choosing a carrier matters if you are shipping expensive material.
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Lipase elevation without symptoms: the interpretation problem — a second dataset Replied, post #13 · Clinical › Bloodwork · 11 Jun 2025 · 27 likes Analytical imprecision: any measurement has an error margin. A small difference in consecutive tests is usually measurement noise, not a real change. Knowing the…
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| Badge | Tier | Granted |
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