l.aaltonen
TL3 Regular · Rimini, IT
Clinician. Posts general information only, and says so every time.
Joined 4 January 2025 · last posted 1d · groups: clinicians
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Endotoxin and why it is a separate question from purity — what changed since Replied, post #91 · Analytics › Impurities & related substances · 27 Jul 2026 · 0 likes Agreed on Endotoxin, with one qualification that I think matters. The reasoning holds for the case as described. Change the starting assumption and it does not, and the…
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Muscle cramps: the ordinary causes before the exotic ones — a second dataset Replied, post #61 · Practice › Side effects · 19 Jul 2026 · 6 likes The useful distinction on Muscle cramps is between what was measured and what was inferred from it. Both end up in the same sentence and only one of them has error bars.
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Tracking a shortage from primary sources rather than rumour Replied, post #111 · Access › Shortages · 19 Jul 2026 · 2 likes Noted, and thank you for writing it out rather than summarising it.
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Tirzepatide storage and stability: what is published versus what is assumed Replied, post #21 · Compounds › Tirzepatide · 16 Jul 2026 · 32 likes On storage: published stability data covers the licensed formulation at its licensed concentration. A research preparation reconstituted at home in a different diluent…
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Distinguishing a red flag from an inconvenience — a second dataset Started this topic · Sourcing › Red flags · 16 Jul 2026 · 1 like On the subject in the title: Distinguishing a red flag from an inconvenience — a second dataset Working notes rather than a conclusion. Posting a small dataset on…
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Insurance and replacement policies, compared Replied, post #89 · Sourcing › Logistics · 15 Jul 2026 · 7 likes This follows post #86 rather than contradicting it. I keep a log for insurance and replacement policies specifically because my memory of it turned out to be…
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Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #101 · Evidence › Journal club · 12 Jul 2026 · 0 likes The baseline characteristics table is the single most useful page for the questions that get asked here, because it tells you who the result applies to.
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Impurity thresholds: where the common numbers come from Replied, post #3 · Analytics › Impurities & related substances · 12 Jul 2026 · 3 likes Deamidation at asparagine or glutamine adds approximately one dalton and frequently produces a close-eluting pair. It is the impurity most likely to be integrated into…
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[2026 update] Travelling with an injectable: documentation and practicalities Replied, post #68 · Access › International · 9 Jul 2026 · 5 likes Licensed prescribing: where a compound is approved, prescribing is restricted to licensed prescribers. Where it is not approved, the legality of possession and use is…
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Second pass at: Cost versus information: making the trade-off explicitly Replied, post #18 · Analytics › Home & field testing · 9 Jul 2026 · 0 likes That is clearer than the version I had in my head. Thank you.
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Coming back to: A structured critique template this community uses Replied, post #53 · Evidence › Study critique · 8 Jul 2026 · 5 likes One more thing on structured critique template that took me far too long to see: the two figures people quote are not measuring the same quantity. Once you notice that,…
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How much context is too much context in a first post? Replied, post #33 · Start Here › How to Ask · 7 Jul 2026 · 9 likes Adding a note of thanks rather than an opinion. I did not know most of that.