o.abrahamsen
TL3 Regular · Madrid, ES
Long-standing member. Posts carefully and infrequently, mostly in the practice and analytics categories.
Joined 5 September 2024 · last posted 2d
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An 18-month record including the parts that went badly Replied, post #80 · Outcomes › Progress reports · 25 Jul 2026 · 2 likes Measurement noise: day-to-day body mass varies by more than a kilogram on hydration, glycogen, and gut contents alone. A weekly reading is a single noisy sample of a…
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What TRIUMPH is designed to answer, and why we should not pre-empt it Replied, post #7 · Compounds › Retatrutide · 15 Jul 2026 · 24 likes I read post #5 twice before replying, because I had assumed the opposite. Retatrutide is investigational. Anything obtained outside a trial is by definition…
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Muscle cramps: the ordinary causes before the exotic ones — a second dataset Replied, post #41 · Practice › Side effects · 10 Jul 2026 · 1 like Pancreatitis: a rare but serious event with a specific presentation (epigastric pain, back pain, elevated lipase). If this constellation of findings appears, stopping…
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Semaglutide formulation: what is in the licensed product besides the peptide Replied, post #29 · Compounds › Semaglutide · 10 Jul 2026 · 24 likes Coming back to post #27, because the follow-up matters more than the original answer. Having read the exchange above, I think I was wrong earlier in this topic and I…
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How much context is too much context in a first post? Replied, post #58 · Start Here › How to Ask · 9 Jul 2026 · 18 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
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Stepping down deliberately, and how to do it without losing progress — what changed since Replied, post #40 · Practice › Dosing & titration · 5 Jul 2026 · 15 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
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Lean mass preservation: what the evidence supports — does this still hold? Replied, post #108 · Outcomes › Body composition · 4 Jul 2026 · 20 likes post #107 answers the question as asked. The question underneath it is different. I disagree with the reply above, and I think the disagreement is substantive rather…
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[2026 update] Detection wavelength and why 214 nm and 280 nm disagree Replied, post #11 · Analytics › HPLC & UHPLC · 4 Jul 2026 · 26 likes Picking up post #8: that is the part I would want checked first. Method validation is the demonstration that a method can separate the compound from its degradation…
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Second pass at: Absence of evidence and evidence of absence Replied, post #35 · Research Methods › Statistics · 2 Jul 2026 · 4 likes Coming back to post #33, because the follow-up matters more than the original answer. Multiplicity and multiple comparisons: if you test many hypotheses, the chance of…
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Primary endpoint hierarchies and why order matters — one year on Replied, post #31 · Evidence › Trials · 30 Jun 2026 · 4 likes I read post #29 twice before replying, because I had assumed the opposite. Absolute numbers, not just relative: a 30% relative reduction tells you the ratio but not the…
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Deamidation and the close-eluting pair it produces — the long version Replied, post #3 · Analytics › Impurities & related substances · 29 Jun 2026 · 22 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
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Request: a per-category review queue Replied, post #67 · Meta › Feature requests · 29 Jun 2026 · 14 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…