p.ostergaard

TL2 Moderator · Dijon

Contributes reviews on supplier material. Based in Dijon.

Joined 12 August 2025 · last posted 3d

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Coming back to: Preparing for an appointment: one page, three questions Replied, post #51 · Clinical › Prescriber conversations · 25 Jul 2026 · 14 likes This follows post #48 rather than contradicting it. Understanding stopping rules: what would prompt stopping the compound? Adverse effect, lack of benefit after a…
Revisiting: Taste changes and food aversion, reported and discussed Replied, post #25 · Practice › Side effects · 25 Jul 2026 · 13 likes Lean mass loss: the rate of lean tissue loss depends on protein intake, resistance training volume, and total energy deficit. Adequate protein and maintaining training…
Pooling trials with different estimands Replied, post #125 · Evidence › Meta-analyses · 24 Jul 2026 · 0 likes On post #121 — agreed on the reasoning, with one qualification. Number needed to treat from a meta-analysis: can be computed from the pooled estimate if the baseline…
Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Replied, post #73 · Evidence › Journal club · 23 Jul 2026 · 2 likes Worth separating two things that post #69 runs together. SURMOUNT-1 (N Engl J Med 2022): Tirzepatide obesity trial. The largest mean weight reduction for a…
Why the timeline is on the right and not the left — what changed since Replied, post #73 · Meta › Site feedback · 13 Jul 2026 · 4 likes post #72 is right about the mechanism and I think understates the practical bit. Moderation decisions: if you disagree with a moderation decision, raising it here gives…
Substitution between formats during a shortage — what changed since Replied, post #6 · Access › Shortages · 10 Jul 2026 · 0 likes Patient advocacy during shortages: some advocacy groups advocate for patients during shortages. Knowing who they are and following their communication is useful.
Revisiting: Protein density versus volume when you cannot eat much Replied, post #46 · Nutrition & Training › Protein & intake · 9 Jul 2026 · 23 likes This follows post #43 rather than contradicting it. Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still…
Osteoarthritis and mechanical versus metabolic improvement — one year on Replied, post #5 · Clinical › Comorbidities · 9 Jul 2026 · 0 likes This follows post #2 rather than contradicting it. Comorbidity control: if a comorbidity (high blood pressure, high lipids) is not adequately controlled, the decision…
Spreadsheets: an appreciation — what changed since Replied, post #80 · Lounge › Off topic · 24 Jun 2026 · 0 likes On post #76 — agreed on the reasoning, with one qualification. Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what…
Stepping down deliberately, and how to do it without losing progress — what changed since Replied, post #11 · Practice › Dosing & titration · 22 Jun 2026 · 0 likes I read post #9 twice before replying, because I had assumed the opposite. The arithmetic of an intermediate dose: if the label says 1.0 mg and 2.0 mg, a dose strictly…
Follow-up: Sleep quality changes during weight loss Replied, post #51 · Wellbeing › Sleep · 22 Jun 2026 · 20 likes Apnoea monitoring: if you have diagnosed or suspected sleep apnoea, periodic monitoring (annually) during weight loss is prudent because severity changes.
Why we ask for units every single time, with three examples of what goes wrong Replied, post #49 · Start Here › How to Ask · 17 Jun 2026 · 12 likes post #48 answers the question as asked. The question underneath it is different. For anyone arriving from a search: the marked solution above is the direct answer, and…