r.mcalister
TL3 Regular · Glasgow, UK
Retired process engineer. Interested in variability: between batches, between people, between weeks.
Joined 30 September 2024 · last posted 6d
132Posts here
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1Solutions
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Most-liked posts
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A plateau that disappeared when I changed how I measured Replied, post #26 · Outcomes › Progress reports · 24 Mar 2026 · 32 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
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Second pass at: Historical amylin analogues and what happened to them Replied, post #14 · Compounds › Cagrilintide & amylin analogues · 17 Jan 2025 · 32 likes On post #10 — agreed on the reasoning, with one qualification. Nausea profile of amylin analogues: the historical agent pramlintide required multiple daily doses and…
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Packaging that arrived damaged: documenting it properly Replied, post #34 · Sourcing › Logistics · 1 Jul 2026 · 31 likes At what point is a parcel genuinely a problem: if it was despatched weeks ago and there has been no update for days at customs, it might be held or lost. Days of delay…
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Does dual agonism explain the effect size, or is it dose? Replied, post #36 · Compounds › Tirzepatide · 14 Jun 2026 · 31 likes SURPASS-2 compared tirzepatide with semaglutide 1.0 mg, the licensed diabetes dose at that time. It did not compare with semaglutide 2.4 mg, the highest approved dose.…
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Publishing an inconvenient result: a case study Replied, post #23 · Sourcing › Independent verification · 22 May 2025 · 31 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
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Tirzepatide in type 2 diabetes: the SURPASS programme, summarised honestly Replied, post #65 · Compounds › Tirzepatide · 20 Apr 2025 · 31 likes I read post #63 twice before replying, because I had assumed the opposite. SURMOUNT-4 used a randomised withdrawal design: everyone titrated, then those on maintenance…
Where this member posts
Badges earned, in order
| Badge | Tier | Granted |
|---|---|---|
| First Reply | bronze | 1 Oct 2024 |
| Basic User | bronze | 4 Oct 2024 |
| Read the Guidelines | bronze | 6 Oct 2024 |
| Welcome | bronze | 9 Oct 2024 |
| First Link | bronze | 15 Oct 2024 |
| First Topic | bronze | 18 Oct 2024 |
| First Quote | bronze | 21 Oct 2024 |
| Editor | bronze | 31 Oct 2024 |
| First Tag | bronze | 2 Nov 2024 |
| Member | bronze | 5 Nov 2024 |
| Sourced | bronze | 5 Dec 2024 |
| Generous | bronze | 21 Dec 2024 |
| Reader | bronze | 25 Dec 2024 |
| First Solution | bronze | 11 Jan 2025 |
| Popular Link | silver | 12 Jan 2025 |
| Regular | silver | 13 Feb 2025 |
| Well Sourced | silver | 9 Mar 2025 |
| Nice Post | bronze | 28 Mar 2025 |
| Good Post | silver | 5 Jun 2025 |
| Documented a Red Flag | silver | 9 Jun 2025 |
| Batch Logger | silver | 25 Jun 2025 |
| Thank You | silver | 23 Jul 2025 |
| Anniversary | silver | 30 Sep 2025 |