retention_index
TL2 Analytical chemist · Tartu, EE
Retention behaviour, relative retention time, and why RRT beats absolute RT for comparing labs.
Joined 6 December 2024 · last posted 2d · groups: analytical-chemists
66Posts here
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Request: show the solution author in the topic list — what changed since Replied, post #66 · Meta › Feature requests · 3 May 2026 · 29 likes Effort estimation: some features are trivial to implement; others are substantial work. Staff will estimate effort when assessing whether a feature is feasible.
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Nausea profile of amylin analogues compared with GLP-1 agonists Replied, post #56 · Compounds › Cagrilintide & amylin analogues · 10 Mar 2026 · 29 likes Worth separating two things that post #52 runs together. The dosing interval: cagrilintide's half-life is roughly 7 to 8 days, suitable for weekly dosing. The…
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Hepatic impairment and the absence of data Replied, post #12 · Clinical › Special populations · 14 Aug 2025 · 29 likes Coming back to post #10, because the follow-up matters more than the original answer. Pancreatitis history: the compounds can rarely trigger pancreatitis. A history of…
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Gallbladder disease risk with rapid weight loss Replied, post #2 · Clinical › Comorbidities · 17 Aug 2024 · 26 likes Interactions between comorbidities: diabetes and kidney disease together change the risk calculation for hypoglycemia and for medication clearance. They are not…
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Half-life, steady state, and accumulation worked through — a second dataset Replied, post #10 · Pharmacology › Pharmacokinetics · 28 Oct 2025 · 25 likes Accumulation at steady state: with a week-long half-life, steady-state concentration is reached around 4 to 5 half-lives (about 4 to 5 weeks). Before that,…
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Second pass at: Albumin binding and how it produces a long half-life Replied, post #2 · Pharmacology › Pharmacokinetics · 1 Aug 2024 · 25 likes On the opening post — agreed on the reasoning, with one qualification. Half-life: semaglutide ≈ 165–184 hours (about a week). Tirzepatide ≈ 5 days. Liraglutide ≈ 13…
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