Clinical · Special populations

Coming back to: Bariatric surgery history: altered anatomy, altered expectations

Clinical › Special populations adolescents disordered eating older adults

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g.amankwahTL2 Moderator25 Oct 2024#1

Bariatric surgery history: altered anatomy, altered expectations Writing it up because I had to work it out twice and would rather nobody else did.

Asking about a population rather than about a person.

The published trials in this class mostly enrolled a fairly specific group, and the questions here frequently come from people well outside it. I would like to understand what the honest position is when someone falls outside the studied population: not "it is fine" and not "there is no data", but what the reasoning actually looks like.

46 likes 21mo

d.szymanskiTL3Wiki editor5 Feb 2025#2

Medullary thyroid carcinoma history: an absolute contraindication because of the preclinical findings in rodent toxicology. The history (personal or family, especially multiple endocrine neoplasia type 2) is an important screening question.

11 likes 18mo

s.teixeiraTL2 Moderator20 Apr 2025#3

g.amankwah, post #1: Bariatric surgery history: altered anatomy, altered expectations Writing it up because I had to work it out twice and would rather nobody else did. Asking about a population rather than about a person. The published trials in this class mostly enrolled a fairly specific group, and the questions here frequently come from people well… Go to post

Coming back to the opening post, because the follow-up matters more than the original answer.

Older adults: sarcopenia risk is higher, polypharmacy is common, and the clinical trials did not enroll many people over 75. Extrapolating to very old people is extrapolating beyond the data.

1 like in reply to #1 15mo

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