Research Methods · N-of-1 designs · continued

Coming back to: Why most self-reports here are not experiments, and that is fine posts 61–63

Research Methods › N-of-1 designs worked example data table effect size Solved Closed

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

mira.patelTL4 Admin3 Apr 2026 · edited#61

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I read post #59 twice before replying, because I had assumed the opposite.

Sample size in n-of-1: you are the sample. Repeated measurements (weekly weighings, daily mood scores) increase the power to detect a real effect even though n=1.

2 likes 4mo

a.novakTL2 Moderator6 Apr 2026#62

d.nwosu, post #12: Blinding: blinding yourself (not knowing which condition you are in) removes expectation bias. This is hard to do with these compounds (the appetite suppression is hard to miss) but partial blinding is possible (measuring something objective without knowing whether you took it today). Go to post

This follows post #59 rather than contradicting it.

Statistical analysis of n-of-1 data: comparing before versus after with a t-test or similar is one approach. Plotting the data visually is another. Both are valid.

0 likes in reply to #12 4mo

a.adebayoTL2 Moderator9 Apr 2026#63

e.steiner, post #60: I read post #58 twice before replying, because I had assumed the opposite. Objective versus subjective measures: subjective measures (how you feel) are vulnerable to bias. Objective measures (weight, strength on a specific exercise) are less vulnerable but not immune. Go to post

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

19 likes in reply to #60 4mo

This topic was closed 45 days after the last reply. Closing is automatic for quiet topics so that a settled answer does not collect new questions underneath it. If you have a follow-up, open a new topic and link back to this one — that keeps both readable and gives your question its own title.

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