The Peptide CommonsEst. May 2024
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Tags · Evidence

confounding

A third variable explaining an apparent association.

48 topics 19 solved Group: Evidence

Related in this group: STEP programme · SURMOUNT programme · SURPASS programme · SELECT trial · FLOW trial · SOUL trial · TRIUMPH programme · PIONEER programme · SUSTAIN programme · LEADER trial · randomised trial · meta-analysis

48 topics · page 1 of 2

TopicParticipantsRepliesViewsActivity
Cleaning a self-reported dataset and what you throw away — what changed since
Posting this under the heading it deserves: Cleaning a self-reported dataset and what you throw away — what changed since Everything below is what sits behind that. Posting the method first, because I know…
HMSCPW 2 2k 1h
About the N-of-1 designs category
Designing a personal experiment that could actually change your mind, including washouts and blinding. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is…
OBDOKAGRIA 4 22k 14h
A structured critique template this community uses — a second dataset
On the subject in the title: A structured critique template this community uses — a second dataset Working notes rather than a conclusion. Session topic: SELECT ( N Engl J Med , 2023). Please read it before…
PRFLKBACAW+47 51 16k 15h
Second pass at: Absence of evidence and evidence of absence
On the subject in the title: Second pass at: Absence of evidence and evidence of absence Working notes rather than a conclusion. Session topic: SELECT ( N Engl J Med , 2023). Please read it before posting;…
SLMFEMRHSR+50 55 18k 16h
A critique that turned out to be unfair, retracted by its author
Posting this under the heading it deserves: A critique that turned out to be unfair, retracted by its author Everything below is what sits behind that. Session topic: SURMOUNT-4 ( JAMA , 2024). Please read it…
MSASFIONS+34 38 20k 17h
Coming back to: A structured critique template this community uses
Posting this under the heading it deserves: A structured critique template this community uses Everything below is what sits behind that. Comparing STEP 8 ( JAMA , 2022) with SURMOUNT-1 ( N Engl J Med , 2022)…
SOFAKHASMY+63 69 17k 18h
A community side-effect dataset, with its response rate and biases
A community side-effect dataset, with its response rate and biases — setting out what I have, and where I think it stops being reliable. Posting the method first, because I know what the first three replies…
SBSPGC 2 5.1k 19h
Immortal time bias in a claims-database study — one year on
Posting this under the heading it deserves: Immortal time bias in a claims-database study — one year on Everything below is what sits behind that. Comparing SURPASS-2 ( N Engl J Med , 2021) with SURMOUNT-1 (…
VMDMMGRPT+41 46 3.7k 22h
Blinding yourself: practical methods and their limits — the long version
Blinding yourself: practical methods and their limits — the long version Writing it up because I had to work it out twice and would rather nobody else did. I have seen SURMOUNT-OSA ( N Engl J Med , 2024)…
CTSDNGJEMD+7 11 1.8k 22h
Selection into a registry and what it does to the estimate — a second dataset
Posting this under the heading it deserves: Selection into a registry and what it does to the estimate — a second dataset Everything below is what sits behind that. Session topic: SURMOUNT-4 ( JAMA , 2024).…
PBINVFPES+28 32 1.3k 1d
Cleaning a self-reported dataset and what you throw away
Cleaning a self-reported dataset and what you throw away — setting out what I have, and where I think it stops being reliable. A documentation question rather than an analytical one. I have a certificate in…
SCFISC 2 28k 1d
Washout with a one-week half-life: the arithmetic — does this still hold?
Washout with a one-week half-life: the arithmetic — does this still hold? — that is the question, and I have not found it answered plainly anywhere I have looked. Comparing SURPASS-2 ( N Engl J Med , 2021)…
AFANABANNN+41 45 12k 1d
Blinding yourself: practical methods and their limits
On the subject in the title: Blinding yourself: practical methods and their limits Working notes rather than a conclusion. Comparing PIONEER 6 ( N Engl J Med , 2019) with STEP 4 ( JAMA , 2021) and finding the…
AZMBCRJNC+40 44 33k 5d
What a confidence interval means, from scratch
What a confidence interval means, from scratch — that is the question, and I have not found it answered plainly anywhere I have looked. I have seen STEP 8 ( JAMA , 2022) cited in support of a claim I do not…
MHSNO 2 2.6k 2mo
Whether an aggregate is worth publishing at all: a disputed topic — does this still hold?
Whether an aggregate is worth publishing at all: a disputed topic — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. I would like to understand…
BDHFBWIBOF+14 18 3.4k 2mo
Measurement error in home scales, with a worked standard deviation — the long version
On the subject in the title: Measurement error in home scales, with a worked standard deviation — the long version Working notes rather than a conclusion. Session topic: SURMOUNT-1 ( N Engl J Med , 2022).…
SKRRAWDYJD+96 105 2k 2mo
Pre-registering a personal experiment, seriously — a second dataset
Posting this under the heading it deserves: Pre-registering a personal experiment, seriously — a second dataset Everything below is what sits behind that. I have seen STEP 8 ( JAMA , 2022) cited in support of…
DMVKAFCVCL+60 66 35k 3mo
An ABAB design with a data table and honest limitations — a second dataset
On the subject in the title: An ABAB design with a data table and honest limitations — a second dataset Working notes rather than a conclusion. Session topic: STEP 2 ( Lancet , 2021). Please read it before…
VELIGRAC+106 118 25k 4mo
Measurement error in home scales, with a worked standard deviation
Measurement error in home scales, with a worked standard deviation Writing it up because I had to work it out twice and would rather nobody else did. Comparing SURPASS-4 ( Lancet , 2021) with STEP 1 ( N Engl…
TKSTVMDEB+26 31 4.3k 4mo
Contributing data without breaching anyone's privacy
Contributing data without breaching anyone's privacy Writing it up because I had to work it out twice and would rather nobody else did. I would like to understand what this number means before I repeat it…
CAMFSRDNEM+65 71 839 5mo
Measurement error in a self-reported exposure
Posting this under the heading it deserves: Measurement error in a self-reported exposure Everything below is what sits behind that. Session topic: SURPASS-2 ( N Engl J Med , 2021). Please read it before…
LHCKSVCW+117 129 45k 5mo
An ABAB design with a data table and honest limitations
An ABAB design with a data table and honest limitations Writing it up because I had to work it out twice and would rather nobody else did. Session topic: SURPASS-4 ( Lancet , 2021). Please read it before…
SSDSEF 2 45k 5mo
Designing a personal experiment that could change your mind
Posting this under the heading it deserves: Designing a personal experiment that could change your mind Everything below is what sits behind that. Session topic: STEP 8 ( JAMA , 2022). Please read it before…
MGECFACHG+2 6 695 6mo
Measurement error in home scales, with a worked standard deviation — a second dataset
Measurement error in home scales, with a worked standard deviation — a second dataset — setting out what I have, and where I think it stops being reliable. Comparing FLOW ( N Engl J Med , 2024) with SURPASS-2…
AKKSA 2 13k 7mo
What a confidence interval means, from scratch — the long version
The question in the title: What a confidence interval means, from scratch — the long version I will give what I have already checked below so nobody repeats it. I have seen SURMOUNT-2 ( Lancet , 2023) cited…
OVTSAWCEBW+16 20 2.3k 8mo
Revisiting: Sample size in a voluntary survey: the selection problem
Revisiting: Sample size in a voluntary survey: the selection problem — setting out what I have, and where I think it stops being reliable. Posting the method first, because I know what the first three replies…
RAZAR 2 56k 9mo
Coming back to: A community side-effect dataset, with its response rate and biases
On the subject in the title: A community side-effect dataset, with its response rate and biases Working notes rather than a conclusion. Posting the method first, because I know what the first three replies…
AATSCNPMA+27 31 46k 9mo
Reverse causation in a cohort study of weight and outcome — a second dataset
Reverse causation in a cohort study of weight and outcome — a second dataset Writing it up because I had to work it out twice and would rather nobody else did. Session topic: SURMOUNT-OSA ( N Engl J Med ,…
MRAKANKBVK+112 131 1.5k 10mo
Aggregated purity results across four services, with caveats — a second dataset
Aggregated purity results across four services, with caveats — a second dataset — setting out what I have, and where I think it stops being reliable. Working through the identity arithmetic and I would like…
CWFNHLTHRE+127 151 42k 10mo
Criticising the method without criticising the authors — one year on
On the subject in the title: Criticising the method without criticising the authors — one year on Working notes rather than a conclusion. Session topic: STEP 2 ( Lancet , 2021). Please read it before posting;…
KOSKJNAKSC+16 20 61k 11mo