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Safety · Contraindications · continued

Conditions that change the calculus rather than forbidding it posts 31–33

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

L
LundqvistTL2Member19 Jul 2026#31

Diabetic retinopathy complications: a signal for this was noted in SUSTAIN 6. Current evidence is mixed. The risk is not zero and some caution is appropriate in people with baseline retinopathy.

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FL
f.laurentTL2 Moderator23 Jul 2026#32

History of pancreatitis: these compounds can rarely trigger pancreatitis. History of pancreatitis increases relative risk. That is a relative contraindication, not absolute, but requires monitoring.

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KB
k.bettencourtTL2Member27 Jul 2026#33

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient.

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