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Access · Shortages · continued

Managing an unplanned gap in supply — what changed since posts 31–60

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

YR
y.rahimiTL2 Moderator5 Aug 2025#31

Allocation and rationing: during severe shortages, suppliers might ration allocation to prescribers. Understanding rationing policies from your prescriber matters for planning.

2 likes 12mo
P
preregisteredTL3Research methods6 Aug 2025#32

Compounding during shortages: some jurisdictions allow pharmacy compounding when a marketed product is in shortage. That permission is jurisdiction-specific and time-limited (usually for the duration of the shortage).

0 likes 12mo
JV
j.vogelTL2 Moderator7 Aug 2025#33

On post #29 — agreed on the reasoning, with one qualification.

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

29 likes 12mo
RI
retention_indexTL2Analytical chemist9 Aug 2025 · edited#34
i.grimaldi, post #3: Patient advocacy during shortages: some advocacy groups advocate for patients during shortages. Knowing who they are and following their communication is useful. Go to post

post #33 answers the question as asked. The question underneath it is different.

Managing an unplanned gap: if a shortage causes a gap in treatment, the questions are how long the gap will be and how that affects your condition. Discussing with your clinician is prudent if the gap is weeks or longer.

14 likes in reply to #3 12mo
MA
m.adeyemiTL2 Moderator10 Aug 2025#35

Dose hold versus tapering: if a temporary shortage forces a gap, holding your dose and resuming when supply returns is different from gradually tapering. The two are different decisions.

1 like 12mo
C
chromatogramTL4Analytical chemist12 Aug 2025#36

International supply chains: a shortage in one country does not mean shortage in another. That is why ordering from multiple suppliers before a shortage gets bad is prudent if you can.

0 likes 12mo
EK
e.kuuselaTL2 Moderator13 Aug 2025#37
s.silva, post #15: Dose hold versus tapering: if a temporary shortage forces a gap, holding your dose and resuming when supply returns is different from gradually tapering. The two are different decisions. Go to post

Worth separating two things that post #33 runs together.

Shortage predictions: regulators and suppliers issue shortage alerts before they become acute. Checking the regulatory website for shortages gives you advance notice.

21 likes in reply to #15 11mo
JM
j.mwangiTL4 Moderator14 Aug 2025#38
c.draganov, post #8: Worth separating two things that post #4 runs together. Shortage predictions: regulators and suppliers issue shortage alerts before they become acute. Checking the regulatory website for shortages gives you advance notice. Go to post

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

9 likes in reply to #8 11mo
EN
e.nilsenTL2 Moderator16 Aug 2025#39
z.laurent, post #21: Compounding during shortages: some jurisdictions allow pharmacy compounding when a marketed product is in shortage. That permission is jurisdiction-specific and time-limited (usually for the duration of the shortage). Go to post

Coming back to post #37, because the follow-up matters more than the original answer.

Resuming after a gap: after a gap of days or a few weeks, most people resume at the dose they were on when they stopped. Gaps of months might require retitration discussion with a clinician.

0 likes in reply to #21 11mo
FT
fr.translation_moTL2Translator · FR17 Aug 2025#40

Picking up post #37: that is the part I would want checked first.

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient.

30 likes 11mo
PE
ppm_errorTL3Analytical chemist18 Aug 2025#41

Resuming after a gap: after a gap of days or a few weeks, most people resume at the dose they were on when they stopped. Gaps of months might require retitration discussion with a clinician.

0 likes 11mo
RP
r.petrovTL2 Moderator20 Aug 2025#42

Shortage predictions: regulators and suppliers issue shortage alerts before they become acute. Checking the regulatory website for shortages gives you advance notice.

5 likes 11mo
MS
m.strand_rphTL3Pharmacist21 Aug 2025#43
a.weiss, post #17: I read post #15 twice before replying, because I had assumed the opposite. Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive. Go to post

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

20 likes in reply to #17 11mo
BV
b.vanheckeTL2 Moderator22 Aug 2025 · edited#44

Worth separating two things that post #40 runs together.

Dose hold versus tapering: if a temporary shortage forces a gap, holding your dose and resuming when supply returns is different from gradually tapering. The two are different decisions.

0 likes 11mo
JM
j.mwangiTL4 Moderator24 Aug 2025#45
Staff post. Actions described here are recorded in the public moderation log and may be challenged in Meta.

Picking up post #42: that is the part I would want checked first.

Patient advocacy during shortages: some advocacy groups advocate for patients during shortages. Knowing who they are and following their communication is useful.

2 likes 11mo
DE
d.eriksenTL2 Moderator25 Aug 2025#46
b.vanhecke, post #44: Worth separating two things that post #40 runs together. Dose hold versus tapering: if a temporary shortage forces a gap, holding your dose and resuming when supply returns is different from gradually tapering. The two are different decisions. Go to post

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

8 likes in reply to #44 11mo
NH
n.haddadTL2 Moderator26 Aug 2025#47
n.lehtinen, post #14: Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up. Go to post

International supply chains: a shortage in one country does not mean shortage in another. That is why ordering from multiple suppliers before a shortage gets bad is prudent if you can.

27 likes in reply to #14 11mo
SC
s.coelhoTL2 Moderator28 Aug 2025#48

Communication from suppliers: a supplier having supply problems usually communicates them. If a supplier goes silent, that is itself information.

0 likes 11mo
JN
j.nwosuTL2 Moderator29 Aug 2025#49

This follows post #46 rather than contradicting it.

Managing an unplanned gap: if a shortage causes a gap in treatment, the questions are how long the gap will be and how that affects your condition. Discussing with your clinician is prudent if the gap is weeks or longer.

0 likes 11mo
NS
n.stanescuTL2 Moderator30 Aug 2025#50
m.strand_rph, post #43: For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use. Go to post

I read post #48 twice before replying, because I had assumed the opposite.

Supply interruptions: official shortage notices are published by regulatory agencies. That is the correct primary source rather than pharmacy rumors or forum discussion.

0 likes in reply to #43 11mo
ED
e.dalgleishTL3Regular31 Aug 2025#51

Compounding during shortages: some jurisdictions allow pharmacy compounding when a marketed product is in shortage. That permission is jurisdiction-specific and time-limited (usually for the duration of the shortage).

0 likes 11mo
AK
ar.kravchenkoTL2 Moderator2 Sep 2025#52

Allocation and rationing: during severe shortages, suppliers might ration allocation to prescribers. Understanding rationing policies from your prescriber matters for planning.

27 likes 11mo
EM
endpoint_marginTL2Member3 Sep 2025#53
v.bruun, post #9: Resuming after a gap: after a gap of days or a few weeks, most people resume at the dose they were on when they stopped. Gaps of months might require retitration discussion with a clinician. Go to post

I read post #51 twice before replying, because I had assumed the opposite.

Communication from suppliers: a supplier having supply problems usually communicates them. If a supplier goes silent, that is itself information.

8 likes in reply to #9 11mo
BT
b.teixeiraTL2 Moderator4 Sep 2025#54

This follows post #51 rather than contradicting it.

International supply chains: a shortage in one country does not mean shortage in another. That is why ordering from multiple suppliers before a shortage gets bad is prudent if you can.

2 likes 11mo
M
MJayawardenaTL3Regular6 Sep 2025#55

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

0 likes 11mo
NZ
n.zielinskiTL2 Moderator7 Sep 2025#56

post #55 answers the question as asked. The question underneath it is different.

Compounding during shortages: some jurisdictions allow pharmacy compounding when a marketed product is in shortage. That permission is jurisdiction-specific and time-limited (usually for the duration of the shortage).

19 likes 11mo
O
OTeixeiraTL3Regular8 Sep 2025#57
e.kimani, post #16: post #15 is right about the mechanism and I think understates the practical bit. Managing an unplanned gap: if a shortage causes a gap in treatment, the questions are how long the gap will be and how that affects your condition. Discussing with your clinician is prudent if the gap is weeks or longer. Go to post

Coming back to post #55, because the follow-up matters more than the original answer.

Dose hold versus tapering: if a temporary shortage forces a gap, holding your dose and resuming when supply returns is different from gradually tapering. The two are different decisions.

5 likes in reply to #16 11mo
SO
s.oyelaranTL2 Moderator9 Sep 2025 · edited#58
i.grimaldi, post #3: Patient advocacy during shortages: some advocacy groups advocate for patients during shortages. Knowing who they are and following their communication is useful. Go to post

Managing an unplanned gap: if a shortage causes a gap in treatment, the questions are how long the gap will be and how that affects your condition. Discussing with your clinician is prudent if the gap is weeks or longer.

0 likes in reply to #3 11mo
O
OkaforTL311 Sep 2025#59
IO
i.oseiTL2 Moderator12 Sep 2025#60

post #59 is right about the mechanism and I think understates the practical bit.

Shortage predictions: regulators and suppliers issue shortage alerts before they become acute. Checking the regulatory website for shortages gives you advance notice.

0 likes 10mo