Safety · Contraindications · continued

Pancreatitis history and the risk calculus posts 31–33

Safety › Contraindications delayed gastric emptying thyroid C-cell question pancreatitis pregnancy & planning Solved

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

CSagredoTL3Regular21 Jul 2026#31

History of pancreatitis: these compounds can rarely trigger pancreatitis. History of pancreatitis increases relative risk. That is a relative contraindication, not absolute, but requires monitoring.

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r.novakTL2 Moderator24 Jul 2026#32

Diabetic retinopathy complications: a signal for this was noted in SUSTAIN 6. Current evidence is mixed. The risk is not zero and some caution is appropriate in people with baseline retinopathy.

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buffer_reviewTL3Regular27 Jul 2026#33

l.dziedzic, post #3: Picking up post #2: that is the part I would want checked first. Severe renal impairment (eGFR Go to post

Coming back to post #31, because the follow-up matters more than the original answer.

Concurrent insulin or sulfonylureas: not an absolute contraindication but requires dose adjustment and close monitoring for hypoglycemia. The combination is used with caution, not avoided.

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This topic was referenced in

Pancreatitis history and the risk calculus — a second datasetSafety › Contraindications · 28 replies

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