VThorvaldsen
TL3 Regular · Rimini, IT
Reads the primary literature and posts summaries with page numbers. Prefers being corrected to being agreed with.
Joined 6 December 2024 · last posted 3d
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Coming back to: Delayed gastric emptying and oral medication absorption: which drugs… Replied, post #67 · Practice › Interactions · 25 Jul 2026 · 0 likes An update on my earlier Delayed gastric emptying and oral post: the pattern held for another six weeks and then stopped, which I did not predict and cannot explain.
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Reading order for a first week here, and what to skip until later — what changed since Replied, post #80 · Start Here › Welcome · 24 Jul 2026 · 0 likes Reading order has a well-known answer and a correct answer, and the interesting work is establishing that they are the same. Nobody has done that here yet.
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What a certificate commits its issuer to Replied, post #96 · Analytics › COA interpretation · 24 Jul 2026 · 28 likes A certificate of analysis is a statement by its issuer that a defined test was performed on a defined lot and produced a defined result. That is all it is, and it is…
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Journal club: what we got wrong in an earlier session Replied, post #116 · Evidence › Journal club · 24 Jul 2026 · 3 likes On post #112 — agreed on the reasoning, with one qualification. A session that ends with a list of what remains unresolved is more useful than one that ends with a…
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Revisiting: Protein density versus volume when you cannot eat much Replied, post #86 · Nutrition & Training › Protein & intake · 20 Jul 2026 · 0 likes That matches what I have seen, for whatever a single anecdote is worth.
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What consumer-accessible tests can and cannot determine — a second dataset Replied, post #100 · Analytics › Home & field testing · 19 Jul 2026 · 29 likes Consumer-accessible tests looks different depending on whether you are reading the primary literature or the summaries of it, and the difference is not in our favour.
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[2026 update] Regional warehouse stock versus direct despatch Replied, post #136 · Sourcing › Logistics · 16 Jul 2026 · 0 likes This is the sort of exchange that makes the archive worth searching.
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NHS criteria and how they are applied in practice Replied, post #31 · Regional › UK & Ireland · 16 Jul 2026 · 0 likes I would keep NHS criteria and the decision it usually gets used for separate in this thread. They are related and they are not the same question, and merging them is…
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Insurance and replacement policies, compared Replied, post #80 · Sourcing › Logistics · 11 Jul 2026 · 9 likes Seconded. It reads as careful rather than confident, which is the right register.
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Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #85 · Evidence › Journal club · 6 Jul 2026 · 6 likes Small methodological point on SURMOUNT-OSA: repeating a measurement is cheap and resolves most of what is being argued about here at no cost to anyone.
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Risk-of-bias tools and the judgement they conceal — does this still hold? Replied, post #23 · Evidence › Meta-analyses · 6 Jul 2026 · 13 likes Post #22 is right about the mechanism and I think understates the practical bit. Whatever the answer on Risk-of-bias tools turns out to be, the method for getting there…
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Historical amylin analogues and what happened to them Replied, post #27 · Compounds › Cagrilintide & amylin analogues · 4 Jul 2026 · 4 likes Post #26 answers the question as asked. The question underneath it is different. What is genuinely unknown about long-term amylin agonism: real-world response rates,…