a.cardoso

TL2 · Braga

Contributes reviews on supplier material. Based in Braga.

Joined 18 September 2025 · last posted 2d

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Request: a per-category review queue Replied, post #132 · Meta › Feature requests · 26 Jul 2026 · 22 likes Source for the per-category review queue figure, since it was asked for. It is in the discussion rather than the abstract, which is why the version circulating is…
BPC-157: what the rodent literature actually shows, and what it does not — does this… Replied, post #10 · Compounds › Repair & healing peptides · 25 Jul 2026 · 17 likes Appreciated. The plain phrasing does more work here than a longer post would.
Reading a rodent study on a secretagogue without over-extrapolating — the long version Replied, post #59 · Compounds › Secretagogues & GH axis · 24 Jul 2026 · 3 likes What I would check first on Reading a rodent study is whether the thing being measured moved or whether the way of measuring it moved. Those look identical in a graph.
Priming a pen and whether the primed volume is wasted Replied, post #15 · Devices › Pens & autoinjectors · 20 Jul 2026 · 13 likes Priming exists because the needle and the cartridge path contain air after a needle change. Skipping it means the first fraction of the dose is not liquid.
How shortages have affected compounding permissions — does this still hold? Replied, post #28 · Access › Shortages · 19 Jul 2026 · 22 likes I would put moderate confidence on the mainstream reading of shortages and no more. That is not scepticism for its own sake; it is where the sourcing actually stops.
GHRH analogues versus ghrelin mimetics: different mechanisms, conflated discussion Replied, post #46 · Compounds › Secretagogues & GH axis · 17 Jul 2026 · 6 likes Coming back to post #44, because the follow-up matters more than the original answer. A note on scope: what I am saying about GHRH analogues versus ghrelin mimetics…
An 18-month record including the parts that went badly Replied, post #70 · Outcomes › Progress reports · 15 Jul 2026 · 0 likes This follows post #67 rather than contradicting it. Self-reported intake is optimistic in a consistent direction, and saying so in your own report is more credible than…
Immortal time bias in a claims-database study — one year on Replied, post #17 · Evidence › Study critique · 11 Jul 2026 · 18 likes Where I would push back on the Immortal time bias consensus is the confidence, not the direction. The direction looks right. The confidence is borrowed.
Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Replied, post #59 · Evidence › Journal club · 6 Jul 2026 · 23 likes STEP 1 looks different depending on whether you are reading the primary literature or the summaries of it, and the difference is not in our favour.
Revisiting: The report format the maintainers ask for, and why each field is there Replied, post #96 · Sourcing › Vendor reports · 5 Jul 2026 · 0 likes Structured report format: compound, lot, independent testing service, method as reported, result, and the certificate figure for the same lot. One lot is one lot. It…
Receptor desensitisation as a tolerance hypothesis, and its weak evidence Replied, post #26 · Pharmacology › Receptor biology · 24 Jun 2026 · 19 likes Picking up post #23: that is the part I would want checked first. Endogenous versus pharmacological receptor engagement differ in magnitude and in duration by orders of…
Follow-up: Sleep quality changes during weight loss Replied, post #37 · Wellbeing › Sleep · 4 Jun 2026 · 0 likes Worth separating two things that post #33 runs together. The published data on sleep outcomes in this class is thinner than the volume of discussion, which is worth…