a.mwangi
TL2 Moderator · Łódź
Contributes reviews on supplier material. Based in Łódź.
Joined 8 April 2025 · last posted 4d
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Common supplements people ask about, assessed one at a time Replied, post #93 · Practice › Interactions · 24 Jul 2026 · 11 likes Food interactions: most interactions are absorption interactions. Some medications absorb better with food, others better on an empty stomach. With an incretin agonist…
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Journal club: SUSTAIN 6 and its retinopathy signal Replied, post #96 · Evidence › Journal club · 21 Jul 2026 · 0 likes SOUL (N Engl J Med 2025): Oral semaglutide cardiovascular outcomes. Extends the cardiovascular evidence to the oral formulation. Note that oral bioavailability is lower…
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Reading order for a first week here, and what to skip until later — what changed since Replied, post #65 · Start Here › Welcome · 20 Jul 2026 · 11 likes Worth separating two things that post #61 runs together. Trust levels accumulate over time and they give you access to small things like the ability to edit your own…
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Priming a pen and whether the primed volume is wasted Replied, post #11 · Devices › Pens & autoinjectors · 18 Jul 2026 · 8 likes Needle installation: some pens require a fresh needle for each injection; others have a single needle that stays attached. Check the design of your pen.
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Mass error in ppm: the arithmetic and the caveat — a second dataset Replied, post #21 · Analytics › Mass spectrometry · 17 Jul 2026 · 26 likes post #20 is right about the mechanism and I think understates the practical bit. Mass accuracy is expressed in parts per million. It is the difference between observed…
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Second pass at: Sleep apnoea improving and the equipment implications Replied, post #86 · Wellbeing › Sleep · 15 Jul 2026 · 0 likes Sleep quality versus quantity: some people report changes to sleep duration; others report changes to sleep quality without duration change. Both can matter for…
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Primary endpoint hierarchies and why order matters — one year on Replied, post #40 · Evidence › Trials · 9 Jul 2026 · 0 likes Surrogate endpoints: an endpoint that is not the outcome that matters but is measured as a stand-in. HbA1c is a surrogate for long-term glucose control and the…
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Immortal time bias in a claims-database study — one year on Replied, post #13 · Evidence › Study critique · 8 Jul 2026 · 12 likes Worth separating two things that post #9 runs together. Choosing the worst interpretation: "The confidence interval includes a harmful effect" is true if the CI goes…
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Lean mass preservation: what the evidence supports — does this still hold? Replied, post #109 · Outcomes › Body composition · 6 Jul 2026 · 13 likes Ultrasound: thickness of subcutaneous fat at specific sites. Less standardised than DXA and operator-dependent. Useful as a supplementary measure but not as a primary…
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Stepping down deliberately, and how to do it without losing progress — what changed since Replied, post #37 · Practice › Dosing & titration · 4 Jul 2026 · 0 likes Coming back to post #35, because the follow-up matters more than the original answer. Reaching a dose and staying there for a year: the question of whether a stable…
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Why we ask for units every single time, with three examples of what goes wrong Replied, post #86 · Start Here › How to Ask · 1 Jul 2026 · 11 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
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Molecular mass of semaglutide and why the figure differs between sources Replied, post #90 · Compounds › Semaglutide · 30 Jun 2026 · 3 likes The STEP programme populations were selected: enrollment criteria required baseline body mass index over 30, no recent blood pressure crisis, no recent retinopathy, no…