an.kirchner
TL2 Moderator · Rosario
Contributes reviews on supplier material. Based in Rosario.
Joined 23 September 2024 · last posted 2d
98Posts here
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1Solutions
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Hypertension improvement and when medication needs revisiting — a second dataset Replied, post #100 · Clinical › Comorbidities · 25 Oct 2024 · 33 likes Type 2 diabetes: the population with the largest evidence base for these compounds. The SURPASS and SUSTAIN programmes established glycaemic benefit. The renal and…
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The topic list is dense — is that deliberate? Replied, post #20 · Meta › Site feedback · 31 Aug 2024 · 32 likes Feature requests: if the site would work better with a feature it does not have (better search, different filtering, new section) suggest it here with the reasoning.
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Coming back to: Washout: how long is long enough, and for what purpose Replied, post #58 · Pharmacology › Pharmacokinetics · 2 Mar 2026 · 30 likes Hepatic metabolism: the degree to which each compound is hepatically metabolised versus renally cleared is known but varies. Severe liver disease changes clearance.
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Tracking a preprint to publication: a worked example — the long version Replied, post #4 · Evidence › Preprints · 31 May 2024 · 30 likes Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has…
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Publication bias detection and its low power — does this still hold? Replied, post #7 · Evidence › Meta-analyses · 16 Jan 2026 · 29 likes Why forest plots are more informative than pooled numbers: they show the variation across studies, which tells you whether the effect is consistent or heterogeneous. A…
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Blinding yourself: practical methods and their limits Replied, post #23 · Research Methods › N-of-1 designs · 5 May 2026 · 28 likes Designing a personal experiment that could actually change your mind: that is the standard for an n-of-1 design. An experiment designed so that any result confirms what…
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Badges earned, in order
| Badge | Tier | Granted |
|---|---|---|
| Basic User | bronze | 26 Sep 2024 |
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| Good Post | silver | 30 Jan 2025 |
| First Vendor Report | bronze | 25 Feb 2025 |
| Consistently Generous | silver | 25 Mar 2025 |
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| Anniversary | silver | 23 Sep 2025 |
| De-escalator | gold | 30 Nov 2025 |