e.mensa
TL2 Moderator · Recife
Contributes reviews on supplier material. Based in Recife.
Joined 18 May 2025 · last posted 2d
95Posts here
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Distinguishing a deletion sequence by mass alone Replied, post #100 · Analytics › Mass spectrometry · 17 Feb 2025 · 32 likes Desalting before analysis: some samples need desalting to remove salts that suppress the peptide signal. Report whether desalting was used, because it can affect the…
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Counter-ion content and its effect on measured mass Replied, post #13 · Analytics › Mass spectrometry · 8 Apr 2025 · 30 likes Coming back to post #11, because the follow-up matters more than the original answer. Mass accuracy is expressed in parts per million. It is the difference between…
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Coming back to: Washout: how long is long enough, and for what purpose Replied, post #26 · Pharmacology › Pharmacokinetics · 27 Jan 2026 · 29 likes Albumin binding: semaglutide binds albumin through a fatty side chain, which sequesters the free form and extends the half-life. Tirzepatide also has albumin binding…
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Sequence verification for an obscure compound: how it is done Replied, post #9 · Compounds › Other compounds · 9 Apr 2025 · 27 likes Melanocortin agonists: mechanism involves the melanocortin-4 receptor pathway that regulates appetite. The documented adverse profile includes blood pressure elevation…
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Injecting into an area that has become firm: why not to Replied, post #40 · Practice › Administration · 9 Jun 2026 · 26 likes Pinch or no pinch: the decision depends on needle length and on your own anatomy. A longer needle (8 mm and up) reaches subcutaneous tissue easily without a pinch. A…
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Half-life, steady state, and accumulation worked through — a second dataset Replied, post #31 · Pharmacology › Pharmacokinetics · 4 Dec 2025 · 26 likes Accumulation at steady state: with a week-long half-life, steady-state concentration is reached around 4 to 5 half-lives (about 4 to 5 weeks). Before that,…
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