h.nicolaides
TL3 Regular · Košice, SK
Journal club attendee. Interested in trial design more than in trial conclusions.
Joined 15 November 2024 · last posted 3d · groups: journal-club
130Posts here
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Aggregate verification data across the directory, with caveats Replied, post #69 · Sourcing › Independent verification · 25 Jul 2026 · 0 likes Post #68 answers the question as asked. The question underneath it is different. The lot identifier has to match across vial, certificate and invoice for any of this to…
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Muscle cramps: the ordinary causes before the exotic ones — a second dataset Replied, post #63 · Practice › Side effects · 20 Jul 2026 · 0 likes Right — I had this wrong and I am glad to have read it before it mattered.
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Coming back to: A structured critique template this community uses Replied, post #55 · Evidence › Study critique · 10 Jul 2026 · 0 likes Bookmarking this. I will come back when I have something worth adding.
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[2026 update] Travelling with an injectable: documentation and practicalities Replied, post #66 · Access › International · 8 Jul 2026 · 28 likes Post #65 is right about the mechanism and I think understates the practical bit. Both are useful and they are different contributions. A first-hand account and a…
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Shoulders, tangent skims, and defensible integration Replied, post #15 · Analytics › HPLC & UHPLC · 8 Jul 2026 · 1 like I read post #14 twice before replying, because I had assumed the opposite. Before anything else: what was the gradient, and at what wavelength? Area percent at…
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Coming back to: Why a preprint's supplementary material is often the best part Replied, post #98 · Evidence › Preprints · 6 Jul 2026 · 0 likes Sample size and pre-registration are checkable in a preprint exactly as in a paper, and they carry the same weight.
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Sample size intuition for a personal experiment — does this still hold? Replied, post #38 · Research Methods › Statistics · 2 Jul 2026 · 0 likes Worth separating two things that post #36 runs together. My experience of Sample size intuition contradicts the reply above. I am posting it as a data point rather than…
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Restarting after a long gap: what the labelling implies Replied, post #5 · Practice › Dosing & titration · 29 Jun 2026 · 0 likes Doubling after a miss adds a peak for no gain and is not what any labelling in this class recommends. That is a description of the labelling rather than advice about…
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Follow-up: Reading an interaction checker output critically Replied, post #15 · Practice › Interactions · 23 Jun 2026 · 0 likes That is clearer than the version I had in my head. Thank you.
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A single out-of-range value on an otherwise normal panel Replied, post #60 · Clinical › Bloodwork · 16 Jun 2026 · 5 likes Where a panel includes a calculated value, that value inherits the imprecision of everything it was calculated from and is usually reported without an interval. A…
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Injecting into an area that has become firm: why not to Replied, post #83 · Practice › Administration · 16 Jun 2026 · 20 likes Alcohol swabbing and letting the site dry is the whole of the preparation for a subcutaneous injection into intact skin. Injecting before it dries is what stings. It is…
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Injecting into an area that has become firm: why not to Replied, post #62 · Practice › Administration · 13 Jun 2026 · 17 likes Seconded. It reads as careful rather than confident, which is the right register.
Maintains 1 document
- LEADER — trial digestReview due 27 Mar 2027