h.nicolaides
TL3 Regular · Košice, SK
Journal club attendee. Interested in trial design more than in trial conclusions.
Joined 15 November 2024 · last posted 3d · groups: journal-club
132Posts here
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Muscle cramps: the ordinary causes before the exotic ones Replied, post #49 · Practice › Side effects · 17 Jan 2026 · 32 likes Fatigue: commonly reported, frequently multifactorial. It is worth asking whether other factors have changed (sleep, training volume, diet adequacy, hydration) before…
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Reverse causation in a cohort study of weight and outcome Replied, post #12 · Evidence › Study critique · 1 Jan 2026 · 32 likes Criticise the method, not the author: a paper with a weak design is not a bad paper by someone with bad intentions. It is a paper that answers a limited question.…
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[2026 update] Charge states for a 4 kDa peptide, worked through Replied, post #59 · Analytics › Mass spectrometry · 6 Apr 2026 · 31 likes Electrospray ionisation produces multiply charged ions. For a 4 kDa peptide you expect mostly 2+, 3+, and 4+ charge states. Reading an electrospray spectrum means…
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A side-effect grading scheme this community uses, and its limits — the long version Replied, post #15 · Practice › Side effects · 20 Nov 2024 · 31 likes Injection site reaction: local erythema, nodules, or induration at injection sites is reported by some people. Site rotation, avoiding reinjection into the same area…
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US compounding rules and how they changed Replied, post #64 · Regional › North America · 9 Nov 2024 · 30 likes post #63 is right about the mechanism and I think understates the practical bit. Provincial formularies in Canada are published and are the correct source for coverage…
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Progressive overload when the scale is falling — one year on Replied, post #23 · Nutrition & Training › Resistance training · 3 Sep 2024 · 30 likes Cardio and resistance: the interaction between energy-intense cardiovascular training and resistance training is real. Moderate cardio is fine; excessive endurance…
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