l.vermeulen

TL2 Moderator · Kumasi

Contributes reviews on supplier material. Based in Kumasi.

Joined 19 November 2024 · last posted 1d · groups: translators

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What a simple presence test is genuinely useful for Replied, post #3 · marked as the solution · Analytics › Home & field testing · 27 Jul 2026 · 16 likes Why third-party testing is stronger: a home test run by the person who made the compound is a self-selected result. The test run by a neutral third party removes…
Second pass at: When your prescriber and the evidence disagree Replied, post #54 · Clinical › Prescriber conversations · 22 Jul 2026 · 0 likes Clarifying indication: if a compound is approved for diabetes but you have obesity without diabetes, clarify whether your clinician considers this off-label use and…
Washout with a one-week half-life: the arithmetic — does this still hold? Replied, post #42 · Research Methods › N-of-1 designs · 18 Jul 2026 · 3 likes Designing a personal experiment that could actually change your mind: that is the standard for an n-of-1 design. An experiment designed so that any result confirms what…
Revisiting: Hepatic effects of glucagon receptor agonism: the mechanistic worry Replied, post #5 · Compounds › Retatrutide · 16 Jul 2026 · 0 likes On the opening post — agreed on the reasoning, with one qualification. Dose escalation in the published trials: the protocols started at lower doses and escalated by…
Private prescribing in the UK: what is actually involved Replied, post #62 · Regional › UK & Ireland · 11 Jul 2026 · 14 likes Cross-border arrangements: some people source from other EU countries. Rules on import for personal use are changing post-Brexit. Current status requires checking with…
Specificity, linearity, accuracy, precision, range, robustness — with real criteria Replied, post #41 · Analytics › Method validation · 9 Jul 2026 · 23 likes Coming back to post #39, because the follow-up matters more than the original answer. Linearity: the detector response is proportional to compound concentration across…
Designing a personal experiment that could change your mind — one year on Replied, post #72 · Research Methods › N-of-1 designs · 8 Jul 2026 · 7 likes Worth separating two things that post #68 runs together. Statistical analysis of n-of-1 data: comparing before versus after with a t-test or similar is one approach.…
[2026 update] Detection wavelength and why 214 nm and 280 nm disagree Replied, post #18 · Analytics › HPLC & UHPLC · 7 Jul 2026 · 4 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
How much context is too much context in a first post? Replied, post #17 · Start Here › How to Ask · 5 Jul 2026 · 26 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
Follow-up: Reading an interaction checker output critically Replied, post #32 · Practice › Interactions · 5 Jul 2026 · 3 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
Second pass at: Absence of evidence and evidence of absence Replied, post #32 · Research Methods › Statistics · 28 Jun 2026 · 0 likes Confounding: a third variable explains an apparent association. In randomised data, randomisation balances confounders. In observational data, confounders can be…
Review: a draft on reconstitution arithmetic, with objections — one year on Replied, post #35 · Documentation › Doc review · 28 Jun 2026 · 6 likes Picking up post #32: that is the part I would want checked first. Promoted topic withdrawal: if a promoted topic becomes outdated or inaccurate and the maintainer does…