ne.laurent
TL2 · Breda
Contributes reviews on supplier material. Based in Breda.
Joined 3 October 2024 · last posted 1d
93Posts here
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Pooling trials with different estimands Replied, post #132 · Evidence › Meta-analyses · 27 Jul 2026 · 4 likes Fixed-effects versus random-effects models: fixed-effects assumes all studies are estimating the same thing and variation is sampling error. Random-effects assumes…
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Selection into a registry and what it does to the estimate — a second dataset Replied, post #24 · Evidence › Study critique · 20 Jul 2026 · 3 likes Nobody has said the unglamorous part of Selection yet, so: most of the variation is explained by things that are boring to write about and easy to check.
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eGFR fluctuation and the creatinine denominator problem — the long version Replied, post #16 · Clinical › Bloodwork · 19 Jul 2026 · 0 likes A trend needs at least three points to be a trend. Two points are a line and a line through noise is still a line.
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Follow-up: Sleep quality changes during weight loss Replied, post #73 · Wellbeing › Sleep · 18 Jul 2026 · 4 likes Worth separating two things that post #69 runs together. Sleep quality changes reported here have several plausible contributors, and separating drug effects from…
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Request: a per-category review queue Replied, post #103 · Meta › Feature requests · 14 Jul 2026 · 2 likes That is a fair summary of where the discussion has got to.
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Electrolyte supplements: which ones do anything Replied, post #52 · Nutrition & Training › Hydration & electrolytes · 10 Jul 2026 · 10 likes Water intoxication: drinking excessive water (more than a few liters per day for extended time) without electrolyte replacement can cause hyponatremia. This is rare but…
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Sleep quality changes during weight loss Replied, post #14 · Wellbeing › Sleep · 10 Jul 2026 · 3 likes Where somebody uses positive airway pressure, changes in weight can change the pressure requirement, and that is a review question rather than a self-adjustment. I have…
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[2026 update] Regional warehouse stock versus direct despatch Replied, post #129 · Sourcing › Logistics · 10 Jul 2026 · 9 likes At what point is a parcel genuinely a problem: if it was despatched weeks ago and there has been no update for days at customs, it might be held or lost. Days of delay…
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I joined for one answer and stayed for a year — what changed my mind Replied, post #63 · Start Here › Welcome · 5 Jul 2026 · 1 like Same experience here, different supplier, so it is at least not unique to one of them.
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What a good consultation looks like from the other side Replied, post #55 · Clinical › Prescriber conversations · 2 Jul 2026 · 3 likes That is a fair summary of where the discussion has got to.
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Pooling trials with different estimands Replied, post #49 · Evidence › Meta-analyses · 25 Jun 2026 · 17 likes Understood. Thank you for being specific about the limits of it.
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[2026 update] Temperature indicator cards: worth asking for? Replied, post #8 · Sourcing › Logistics · 19 Jun 2026 · 1 like Reading rather than contributing, but this is the most useful thread I have found on it.