peak_purity
TL3 Analytical chemist · Leiden, NL
Diode-array detection, peak purity, and the difference between "one peak" and "one compound".
Joined 30 July 2024 · last posted 9h · groups: analytical-chemists
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Trust level 3 requirements: a clarification — does this still hold? Replied, post #91 · Meta › Announcements · 28 Jul 2026 · 5 likes One question about the transition rather than the policy: what happens to topics that are in flight when it takes effect? The announcement is clear about posts and…
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Reflectance and photometric devices: precision in practice — a second dataset Replied, post #77 · Analytics › Home & field testing · 20 Jul 2026 · 0 likes Lateral-flow devices: like a rapid COVID test. They have a reagent strip and produce a colour result. They are quick but not precise and not intended for quantitative…
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Follow-up: Reading an interaction checker output critically Replied, post #54 · Practice › Interactions · 19 Jul 2026 · 5 likes Answering the Reading an interaction checker output question as asked, then the question I think is meant. As asked: yes, with the qualification below. As meant: it…
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Follow-up: Comparing two chromatograms from different laboratories, properly Replied, post #62 · Analytics › HPLC & UHPLC · 18 Jul 2026 · 11 likes This is why a purity figure without the underlying chromatogram is weaker evidence than it appears. It is also why two competent laboratories can report different…
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eGFR fluctuation and the creatinine denominator problem — the long version Replied, post #7 · Clinical › Bloodwork · 16 Jul 2026 · 26 likes The version of egfr fluctuation that I was taught turned out to be a teaching simplification. Useful, and not true in the way I had assumed it was.
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What consumer-accessible tests can and cannot determine — a second dataset Replied, post #89 · Analytics › Home & field testing · 15 Jul 2026 · 8 likes Second-hand on consumer-accessible tests, so weight it accordingly — someone whose method I trust told me this and I have not verified it myself.
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Coming back to: Preparing for an appointment: one page, three questions Replied, post #2 · Clinical › Prescriber conversations · 15 Jul 2026 · 0 likes Picking up the opening post: that is the part I would want checked first. If the answer is no, asking for the reason is reasonable and the reason is usually specific.…
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Sulfonylureas: the interaction most worth taking seriously — what changed since Replied, post #6 · Practice › Interactions · 14 Jul 2026 · 4 likes Nothing to add, except that this is the answer I would give if asked.
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Osteoarthritis and mechanical versus metabolic improvement — one year on Replied, post #46 · Clinical › Comorbidities · 12 Jul 2026 · 0 likes Reporting rather than recommending, on Osteoarthritis and mechanical versus metabolic. What happened is above. Whether it should have is a different question and not…
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Journal club: what we got wrong in an earlier session Replied, post #68 · Evidence › Journal club · 9 Jul 2026 · 3 likes I read post #67 twice before replying, because I had assumed the opposite. A session that ends with a list of what remains unresolved is more useful than one that ends…
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[2026 update] Temperature indicator cards: worth asking for? Replied, post #17 · Sourcing › Logistics · 8 Jul 2026 · 17 likes This follows post #15 rather than contradicting it. Temperature indicator cards was covered in the wiki last year and the page has a review date on it, which is a…
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Second pass at: Metformin co-administration and additive GI effects Replied, post #142 · Practice › Interactions · 8 Jul 2026 · 13 likes Metformin co-administration looks different depending on whether you are reading the primary literature or the summaries of it, and the difference is not in our favour.
Maintains 4 documents
- Mazdutide — referenceReview due 17 Oct 2026
- LC-MS identity confirmationReview due 23 Mar 2027
- System suitability testingReview due 1 Dec 2026
- Water content by Karl Fischer titrationReview due 7 Apr 2027