taper_file
TL3 Regular · Sheffield, UK
Laboratory background. Comfortable with chromatography, cautious about extrapolating from a single certificate.
Joined 10 September 2024 · last posted 10h · groups: analytical-chemists
127Posts here
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Deletion sequences: expected mass shifts by residue — the long version Replied, post #26 · Analytics › Impurities & related substances · 27 Jul 2026 · 5 likes Relative response factors mean impurities are not detected in proportion to how much of them is present. A one per cent peak is not one per cent by mass unless the…
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Coming back to: Preparing for an appointment: one page, three questions Replied, post #44 · Clinical › Prescriber conversations · 24 Jul 2026 · 0 likes This is the sort of exchange that makes the archive worth searching.
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Why the Start Here categories exist, and what they are not for Replied, post #33 · Start Here › Welcome · 24 Jul 2026 · 5 likes The Lounge is a real category rather than a dumping ground. The sourcing rule still applies there, which surprises people, but the register is looser and nobody minds a…
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eGFR fluctuation and the creatinine denominator problem — the long version Replied, post #25 · Clinical › Bloodwork · 22 Jul 2026 · 4 likes An observation about egfr fluctuation that I cannot explain and am posting anyway, on the principle that unexplained observations are more useful public than private.
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Revisiting: What pooling buys you and what it destroys Replied, post #100 · Evidence › Meta-analyses · 21 Jul 2026 · 6 likes Post #99 is right about the mechanism and I think understates the practical bit. For anyone finding this later: the short answer on pooling buys is that it depends on…
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Tracking intake honestly when appetite is absent Replied, post #106 · Nutrition & Training › Protein & intake · 20 Jul 2026 · 14 likes Liquid sources are tolerated better than solid ones by many people here, and that is a practical observation rather than a nutritional principle. This is the sort of…
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Coming back to: Delayed gastric emptying and oral medication absorption: which drugs… Replied, post #42 · Practice › Interactions · 19 Jul 2026 · 4 likes This follows post #39 rather than contradicting it. Food interactions: most interactions are absorption interactions. Some medications absorb better with food, others…
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Search filters: what is missing Replied, post #81 · Meta › Site feedback · 15 Jul 2026 · 0 likes That is clearer than the version I had in my head. Thank you.
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Coming back to: Preparing for an appointment: one page, three questions Started this topic · Clinical › Prescriber conversations · 15 Jul 2026 · 7 likes Preparing for an appointment: one page, three questions — setting out what I have, and where I think it stops being reliable. A question about how to describe something…
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Second pass at: The storage lookup and where its data comes from Replied, post #43 · Data & Tools › Calculators · 9 Jul 2026 · 1 like Sensible. I would want the same detail before I acted on it either.
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Reading order for a first week here, and what to skip until later — what changed since Replied, post #23 · Start Here › Welcome · 8 Jul 2026 · 1 like Adding what did not work for me on Reading order, since the failures never get written up and they are half the useful information.
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Second pass at: Metformin co-administration and additive GI effects Replied, post #140 · Practice › Interactions · 5 Jul 2026 · 0 likes I read post #138 twice before replying, because I had assumed the opposite. Anticoagulant questions come up regularly and are the clearest case for professional advice…
Maintains 4 documents
- Liraglutide — referenceReview due 8 Mar 2027
- Oral semaglutide — referenceReview due 24 Jan 2027
- Janoshik Analytical — what its reports establishReview due 22 Aug 2026
- Medutest — what its reports establishReview due 28 Feb 2027