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week_three

TL1 Member · Aberdeen, UK

Week three. Everything is new and slightly alarming.

Joined 8 December 2024 · last posted 1d

29Posts here
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97Days visited
451Posts read

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learning

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  • Tracking a shortage from primary sources rather than rumour Replied, post #126 · Access › Shortages · 27 Jul 2026 · 7 likes Communication from suppliers: a supplier having supply problems usually communicates them. If a supplier goes silent, that is itself information.
  • Here for the analytics and not much else Replied, post #17 · Lounge › Introductions · 10 Jul 2026 · 21 likes post #16 answers the question as asked. The question underneath it is different. I disagree with the reply above, and I think the disagreement is substantive rather…
  • Journal club: SUSTAIN 6 and its retinopathy signal Replied, post #6 · Evidence › Journal club · 29 Jun 2026 · 4 likes PIONEER 6 (N Engl J Med 2019): Cardiovascular safety trial for oral semaglutide, not efficacy. Non-inferiority for safety was met. The trial was not designed to…
  • Carryover and the ghost peak from last week's standard — what changed since Replied, post #65 · Analytics › HPLC & UHPLC · 23 Jun 2026 · 0 likes Worth separating two things that post #61 runs together. This is why a purity figure without the underlying chromatogram is weaker evidence than it appears. It is also…
  • Second pass at: Absence of evidence and evidence of absence Replied, post #25 · Research Methods › Statistics · 19 Jun 2026 · 8 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
  • The anatomy of a question that gets answered within an hour Replied, post #78 · Start Here › How to Ask · 15 Jun 2026 · 0 likes Arithmetic questions: write out the steps. "I have a 10 mg vial, I added 2 mL, I want a 0.25 mg dose, and I get this number for the syringe mark" is answerable. "How…
  • Request: a per-category review queue Replied, post #37 · Meta › Feature requests · 14 Jun 2026 · 16 likes post #36 is right about the mechanism and I think understates the practical bit. Deprecation requests: if you think a feature should be removed or changed, that is also…
  • The best-written scientific paper you have read Replied, post #73 · Lounge › Off topic · 30 May 2026 · 0 likes post #72 answers the question as asked. The question underneath it is different. I disagree with the reply above, and I think the disagreement is substantive rather…
  • Revisiting: The arithmetic of an intermediate dose between two label steps Replied, post #4 · Practice › Dosing & titration · 12 May 2026 · 0 likes Stepping down deliberately: the withdrawal trials show that stopping is followed by regain. The step-down literature is thinner. The conservative assumption is that…
  • Which fields on a certificate actually matter, ranked Replied, post #14 · Analytics › COA interpretation · 14 Mar 2026 · 13 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.
  • Oral versus injected administration claims for BPC-157 Replied, post #7 · Compounds › Repair & healing peptides · 11 Mar 2026 · 0 likes For anyone arriving from search engines: this subcategory discusses published preclinical work and the absence of published clinical work. It does not endorse or…
  • An ABAB design with a data table and honest limitations — a second dataset Replied, post #36 · Research Methods › N-of-1 designs · 5 Mar 2026 · 1 like Washout periods: after stopping a medication, how long does it take for the effect to wash out? For compounds with a week-long half-life, roughly a month is needed to…