z.laurent
TL2 Moderator · Tampere
Contributes reviews on supplier material. Based in Tampere.
Joined 15 January 2025 · last posted 6h
76Posts here
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Hepatic impairment and the absence of data Replied, post #25 · Clinical › Special populations · 2 Sep 2025 · 29 likes Pancreatitis history: the compounds can rarely trigger pancreatitis. A history of pancreatitis makes monitoring for recurrence more important during titration.
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Pooling trials with different estimands Replied, post #74 · Evidence › Meta-analyses · 6 Jul 2026 · 28 likes post #73 answers the question as asked. The question underneath it is different. Number needed to treat from a meta-analysis: can be computed from the pooled estimate…
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Coming back to: Washout: how long is long enough, and for what purpose Replied, post #98 · Pharmacology › Pharmacokinetics · 8 Apr 2026 · 28 likes SNAC (the oral bioavailability enhancer): sodium N-(8-[2-hydroxybenzoyl]amino) caprylate transiently raises gastric pH and promotes absorption. Without it, oral…
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Insurance and replacement policies, compared Replied, post #114 · Sourcing › Logistics · 24 Jul 2026 · 27 likes Tracking stops updating: tracking last updated days ago usually means the package is in transit and will not update until it reaches the next scanning point. No update…
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What a statistical analysis plan adds that the paper does not Replied, post #2 · marked as the solution · Evidence › Trials · 21 Jul 2026 · 26 likes The estimand: what the trial set out to estimate. Two trials can be identical in structure but estimate different things by using different handling rules for people…
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Why the titration planner refuses to produce a schedule below a floor Replied, post #10 · Data & Tools › Calculators · 15 Nov 2025 · 26 likes I read post #8 twice before replying, because I had assumed the opposite. The calculators maintained on this site are open-source and verifiable. They are intended to…
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