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Topic summary

About the Contraindications category

This is a generated summary. It shows the 5 most-liked posts from a topic of 11, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.
ET
e.tammTL2 Moderator21 May 2025#3

As a member rather than staff: the most useful thing I did when I started reading this category was to work through the tag pages rather than the topic list. The topic list shows you what is recent. The tags show you what is settled.

20 likes 14mo
KF
k.farrugiaTL3Regular23 May 2025#4

Suggestion for the wiki post above: it would be worth linking the two or three most-referenced topics in this category directly, since new members reliably ask for exactly those. Happy to make the edit myself if nobody objects, with a revision note.

8 likes 14mo
GA
g.amankwahTL2 Moderator29 May 2025#7

Concurrent insulin or sulfonylureas: not an absolute contraindication but requires dose adjustment and close monitoring for hypoglycemia. The combination is used with caution, not avoided.

14 likes 14mo
BN
bench_notesTL4 Moderator2 Jun 2025#10
outline_first, post #8: Gastroparesis or severe delayed gastric emptying: these compounds slow gastric emptying. Pre-existing severe gastroparesis can be worsened. That is a relative contraindication depending on baseline severity. Go to post
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post #9 answers the question as asked. The question underneath it is different.

Severe renal impairment (eGFR <15): these compounds are renally cleared and accumulate in severe kidney disease. Risk-benefit is unfavourable without dose adjustment.

28 likes in reply to #8 14mo
KA
k.asanteTL2 Moderator4 Jun 2025#11

Disordered eating history: appetite suppression can trigger relapse in people with history of anorexia, bulimia, or other eating disorders. This is a relative contraindication requiring specialist input.

32 likes 14mo

Read the full topic (11 posts)

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