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Data & Tools · Calculators · continued

Coming back to: Feature request: should a dose-equivalence tool exist at all? posts 31–42

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

RM
r.marsdenTL3Regular7 Dec 2025#31

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

5 likes 8mo
NS
n.serranoTL2 Moderator8 Dec 2025#32
t.demir, post #13: Picking up post #10: that is the part I would want checked first. Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up. Go to post

Precision and significant figures: the calculators do not round to match your input precision. If you input values to one decimal place, the output might have more. Use significant figures appropriate to your input precision.

14 likes in reply to #13 8mo
P
PSundbergTL2Member9 Dec 2025#33
h.amankwah, post #24: This follows post #21 rather than contradicting it. Why calculators are not medical advice: they do arithmetic. Medical decisions are not arithmetic. A calculator that says a certain dose is "compatible with" a certain body mass is not a prescription. Go to post

post #32 is right about the mechanism and I think understates the practical bit.

Offline use: all calculators are written in JavaScript and can be downloaded and run offline if desired. They do not require internet connectivity to function.

28 likes in reply to #24 8mo
FF
f.fontaineTL2 Moderator10 Dec 2025#34

Worth separating two things that post #30 runs together.

Reporting bugs: if you notice a calculator giving wrong results, report it in this subcategory. Bugs are fixed when identified.

0 likes 8mo
ST
sterile_tableTL3Regular11 Dec 2025#35

Titration planning: a calculator that shows you the escalation schedule for different starting and ending doses can help you visualize your path. Actual path might be slower or adjusted for tolerability.

2 likes 8mo
YE
y.eriksenTL2 Moderator11 Dec 2025#36
j.nascimento, post #18: Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had been repeating something I had not checked carefully enough. Go to post

Coming back to post #34, because the follow-up matters more than the original answer.

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

9 likes in reply to #18 8mo
CR
curious_readerTL1Member12 Dec 2025 · edited#37

post #36 answers the question as asked. The question underneath it is different.

Reconstitution calculator: enter vial mass, final volume target, and the calculator tells you concentration and syringe mark for a given dose. Useful for double-checking arithmetic when you are doing it by hand.

20 likes 8mo
MR
m.ramosTL2 Moderator13 Dec 2025#38

The calculators maintained on this site are open-source and verifiable. They are intended to check arithmetic, not to replace medical judgement. Using them is optional and they are provided for convenience.

0 likes 7mo
AR
ambient_reviewTL314 Dec 2025#39
AP
a.petrovTL2 Moderator15 Dec 2025 · edited#40
l.parkinson, post #8: Why calculators are not medical advice: they do arithmetic. Medical decisions are not arithmetic. A calculator that says a certain dose is "compatible with" a certain body mass is not a prescription. Go to post

I read post #38 twice before replying, because I had assumed the opposite.

Why calculators are not medical advice: they do arithmetic. Medical decisions are not arithmetic. A calculator that says a certain dose is "compatible with" a certain body mass is not a prescription.

5 likes in reply to #8 7mo
TY
two_year_lineTL3Regular16 Dec 2025#41

Dose equivalence calculator: compounds have different potencies. The calculator is provided with a caveat: "equivalence" is not precise and individual response varies. It is a rough starting point, not a dose prescription.

0 likes 7mo
CC
c.chowdhuryTL2 Moderator16 Dec 2025#42

Mass error checking: enter your observed mass and theoretical mass and check whether the difference in ppm is within reasonable bounds for your instrument. Useful sanity check on LC-MS results.

24 likes 7mo

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