Coming back to: Feature request: should a dose-equivalence tool exist at all? posts 31–42
This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.
Precision and significant figures: the calculators do not round to match your input precision. If you input values to one decimal place, the output might have more. Use significant figures appropriate to your input precision.
post #32 is right about the mechanism and I think understates the practical bit.
Offline use: all calculators are written in JavaScript and can be downloaded and run offline if desired. They do not require internet connectivity to function.
Worth separating two things that post #30 runs together.
Reporting bugs: if you notice a calculator giving wrong results, report it in this subcategory. Bugs are fixed when identified.
Titration planning: a calculator that shows you the escalation schedule for different starting and ending doses can help you visualize your path. Actual path might be slower or adjusted for tolerability.
Coming back to post #34, because the follow-up matters more than the original answer.
Two things before anyone answers the substance.
First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.
post #36 answers the question as asked. The question underneath it is different.
Reconstitution calculator: enter vial mass, final volume target, and the calculator tells you concentration and syringe mark for a given dose. Useful for double-checking arithmetic when you are doing it by hand.
Collapsed as off-topic by two members at trust level 3 or above
This follows post #36 rather than contradicting it.
Units: all calculators explicitly require units to be stated. This prevents the decimal-point errors that come from forgetting units. Always verify units in and out.
I read post #38 twice before replying, because I had assumed the opposite.
Why calculators are not medical advice: they do arithmetic. Medical decisions are not arithmetic. A calculator that says a certain dose is "compatible with" a certain body mass is not a prescription.
Dose equivalence calculator: compounds have different potencies. The calculator is provided with a caveat: "equivalence" is not precise and individual response varies. It is a rough starting point, not a dose prescription.
Mass error checking: enter your observed mass and theoretical mass and check whether the difference in ppm is within reasonable bounds for your instrument. Useful sanity check on LC-MS results.
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