The Peptide CommonsEst. May 2024
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Topic summary

Priming a pen and whether the primed volume is wasted — one year on

This is a generated summary. It shows the 5 most-liked posts from a topic of 8, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.
EP
e.piresTL2 Moderator14 Aug 2024#1

Posting this under the heading it deserves: Priming a pen and whether the primed volume is wasted — one year on Everything below is what sits behind that.

Practical question with the units stated, because I have seen how quickly these go wrong without them.

I have a 5 mg vial of tirzepatide and I am working to a 0.5 mg step. My syringes are U-100 insulin syringes, 0.3 mL barrel.

I can do the arithmetic and I have done it twice, getting the same answer both times, but I would like someone to check the reasoning rather than the number — specifically whether I have thought about the residual volume correctly, and whether the graduation I am landing on is one a person can actually read.

50 likes 23mo
AA
a.almeidaTL2 Moderator Solution2 Sep 2024#3

Off-label dosing with a pen: if you want to deliver a dose different from the pen's pre-set steps (e.g., halfway between two step doses), that is off-label use. Some pens allow it; others do not. Confirm before attempting.

11 likes 23mo
AW
a.weissTL2 Moderator9 Sep 2024#4
a.almeida, post #3: Off-label dosing with a pen: if you want to deliver a dose different from the pen's pre-set steps (e.g., halfway between two step doses), that is off-label use. Some pens allow it; others do not. Confirm before attempting. Go to post

Injection duration: most pens deliver the dose over several seconds. Holding the button down for the full duration ensures complete delivery. Releasing early can result in underdosing.

13 likes in reply to #3 23mo
KR
k.roosTL2 Moderator15 Sep 2024#5

Dose counters: pens show the remaining number of doses. When the counter reaches zero, the pen is empty and cannot deliver more. Noting the counter before injection prevents running out unexpectedly.

20 likes 22mo
IB
i.bakkenTL2 Moderator3 Oct 2024 · edited#8
l.dziedzic, post #6: Worth separating two things that post #2 runs together. Priming: most pens require priming before the first use (injecting a small amount to fill the needle and line). Not priming can result in no dose being delivered on the first injection. Go to post

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

8 likes in reply to #6 22mo

Read the full topic (8 posts)

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