Tags · Practice
cloudy or discoloured solution
Visual inspection findings and what they mean.
Related in this group: reconstitution · bacteriostatic water · sterile water · concentration maths · syringe units · dead volume · titration · dose reduction · missed dose · injection site rotation · needle gauge & length · subcutaneous injection
34 topics · page 1 of 2
| Topic | Participants | Replies | Views | Activity |
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Coming back to: Solubility limits and what a cloudy solution is telling you
On the subject in the title: Solubility limits and what a cloudy solution is telling you Working notes rather than a conclusion. A documentation question rather than an analytical one. I have a certificate in…
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+38 | 43 | 29k | 13h |
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Solubility limits and what a cloudy solution is telling you
Solubility limits and what a cloudy solution is telling you — setting out what I have, and where I think it stops being reliable. A documentation question rather than an analytical one. I have a certificate…
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+11 | 15 | 34k | 20h |
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Coming back to: Storing in the door of the fridge is worse than you think
On the subject in the title: Storing in the door of the fridge is worse than you think Working notes rather than a conclusion. I have read the maintained page on this and I still have a gap, so I am asking…
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+2 | 6 | 2.1k | 1d |
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What published stability data actually covers, and what it does not
Asking directly, because I could not find a straight answer: What published stability data actually covers, and what it does not Reporting something rather than asking about it, in case the pattern is useful…
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+8 | 12 | 435 | 1d |
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Coming back to: Light exposure: how much protection is proportionate?
Asking directly, because I could not find a straight answer: Light exposure: how much protection is proportionate? Practical question with the units stated, because I have seen how quickly these go wrong…
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+5 | 10 | 13k | 2d |
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Preservatives: function, testing, and limits — one year on
On the subject in the title: Preservatives: function, testing, and limits — one year on Working notes rather than a conclusion. Working through the identity arithmetic and I would like it checked. tirzepatide…
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+28 | 32 | 437 | 8d |
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[2026 update] Does a peptide degrade silently, with no visual change?
Does a peptide degrade silently, with no visual change? — that is the question, and I have not found it answered plainly anywhere I have looked. I have read the maintained page on this and I still have a gap,…
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+82 | 86 | 24k | 15d |
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Second pass at: Temperature logging at home: what is worth the effort
Posting this under the heading it deserves: Second pass at: Temperature logging at home: what is worth the effort Everything below is what sits behind that. Reporting something rather than asking about it, in…
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+4 | 8 | 29k | 1mo |
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[2026 update] Storing lyophilised material long term: what governs the shelf life
Storing lyophilised material long term: what governs the shelf life — setting out what I have, and where I think it stops being reliable. A question about technique rather than about dose. I have been doing…
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+122 | 133 | 35k | 1mo |
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Follow-up: A parcel that arrived warm: a decision process, not a verdict
Posting this under the heading it deserves: A parcel that arrived warm: a decision process, not a verdict Everything below is what sits behind that. A question about technique rather than about dose. I have…
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+49 | 59 | 1.2k | 2mo |
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Revisiting: Mean kinetic temperature explained without the mathematics
Revisiting: Mean kinetic temperature explained without the mathematics Writing it up because I had to work it out twice and would rather nobody else did. Practical question with the units stated, because I…
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+67 | 75 | 909 | 2mo |
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Follow-up: Lyophilisation and why the cake looks the way it does
Lyophilisation and why the cake looks the way it does Writing it up because I had to work it out twice and would rather nobody else did. I would like to understand what this number means before I repeat it…
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+10 | 14 | 11k | 3mo |
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Light exposure: how much protection is proportionate?
The question in the title: Light exposure: how much protection is proportionate? I will give what I have already checked below so nobody repeats it. A question about technique rather than about dose. I have…
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2 | 59 | 3mo | |
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[2026 update] Buffers, pH and why a formulation is a formulation
Posting this under the heading it deserves: Buffers, pH and why a formulation is a formulation Everything below is what sits behind that. Working through the identity arithmetic and I would like it checked.…
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2 | 773 | 3mo | |
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Second pass at: Adsorptive losses at low concentration, and why dilute solutions are fragile
On the subject in the title: Second pass at: Adsorptive losses at low concentration, and why dilute solutions are fragile Working notes rather than a conclusion. Practical question with the units stated,…
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+77 | 87 | 58k | 4mo |
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Storing in the door of the fridge is worse than you think
Storing in the door of the fridge is worse than you think Writing it up because I had to work it out twice and would rather nobody else did. A question about technique rather than about dose. I have been…
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2 | 8.3k | 5mo | |
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Adsorption to container surfaces and to plastics
On the subject in the title: Adsorption to container surfaces and to plastics Working notes rather than a conclusion. A documentation question rather than an analytical one. I have a certificate in front of…
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+13 | 17 | 4.3k | 5mo |
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Lyophilisation and why the cake looks the way it does
Posting this under the heading it deserves: Lyophilisation and why the cake looks the way it does Everything below is what sits behind that. I would like to understand what this number means before I repeat…
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+33 | 37 | 60k | 6mo |
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What published stability data actually covers, and what it does not — what changed since
What published stability data actually covers, and what it does not — what changed since — that is the question, and I have not found it answered plainly anywhere I have looked. Practical question with the…
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3 | 43k | 6mo | |
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Temperature logging at home: what is worth the effort
Temperature logging at home: what is worth the effort — setting out what I have, and where I think it stops being reliable. Practical question with the units stated, because I have seen how quickly these go…
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2 | 6.3k | 7mo | |
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Freeze-thaw and why one cycle is not the same as five
On the subject in the title: Freeze-thaw and why one cycle is not the same as five Working notes rather than a conclusion. I have read the maintained page on this and I still have a gap, so I am asking rather…
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+21 | 25 | 41k | 8mo |
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Refrigerated versus room temperature: the trade-off stated plainly — what changed since
Posting this under the heading it deserves: Refrigerated versus room temperature: the trade-off stated plainly — what changed since Everything below is what sits behind that. Practical question with the units…
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2 | 2.7k | 9mo | |
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Power cut for eleven hours: how I assessed it afterwards
Posting this under the heading it deserves: Power cut for eleven hours: how I assessed it afterwards Everything below is what sits behind that. Practical question with the units stated, because I have seen…
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+102 | 109 | 1.4k | 9mo |
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Revisiting: Power cut for eleven hours: how I assessed it afterwards
Revisiting: Power cut for eleven hours: how I assessed it afterwards — setting out what I have, and where I think it stops being reliable. A question about technique rather than about dose. I have been doing…
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4 | 195 | 9mo | |
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Second pass at: Isotonicity and what happens when you get it wrong
Second pass at: Isotonicity and what happens when you get it wrong — setting out what I have, and where I think it stops being reliable. Working through the identity arithmetic and I would like it checked.…
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+1 | 5 | 2.6k | 11mo |
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Excipient function in a licensed injectable
Excipient function in a licensed injectable Writing it up because I had to work it out twice and would rather nobody else did. Posting the method first, because I know what the first three replies will…
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+3 | 7 | 36k | 14mo |
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Preservatives: function, testing, and limits
Preservatives: function, testing, and limits — setting out what I have, and where I think it stops being reliable. Working through the identity arithmetic and I would like it checked. tirzepatide has a…
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+23 | 27 | 3.7k | 16mo |
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Coming back to: Adsorption to container surfaces and to plastics
Adsorption to container surfaces and to plastics — setting out what I have, and where I think it stops being reliable. Posting the method first, because I know what the first three replies will otherwise be.…
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2 | 459 | 17mo | |
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About the Formulation chemistry category
Buffers, pH, isotonicity, preservatives, lyophilisation and excipient function. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its author and…
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4 | 4.5k | 18mo | |
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Transporting a vial for a weekend away
On the subject in the title: Transporting a vial for a weekend away Working notes rather than a conclusion. Practical question with the units stated, because I have seen how quickly these go wrong without…
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+39 | 45 | 35k | 21mo |
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