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Devices · Pens & autoinjectors

A pen that felt like it delivered nothing: diagnosing it afterwards

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Solved by orbitrap_ola in post #5
Reusability: some pens are single-use (throw away after one injection). Others can be reused until empty. Confirm which type you have. Reusing a single-use pen is ineffective because the mechanism does not reset.

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AZ
a.zamoraTL2 Moderator9 Apr 2025#1

On the subject in the title: A pen that felt like it delivered nothing: diagnosing it afterwards Working notes rather than a conclusion.

A question about technique rather than about dose.

I have been doing the same thing for 14 months and it works, and then I read one of the documentation pages here and realised I may have been reasoning from a misunderstanding the whole time. Nothing has gone wrong; I would just like to understand why it has not.

What I do, exactly, is described below. Please tell me which parts are load-bearing and which are superstition.

0 likes 16mo
FW
f.weissTL2 Moderator26 Apr 2025#2

Pen mechanics: most pens are dial-and-inject devices where you dial the dose on the pen and push the button to inject. Understanding your specific pen's mechanism prevents dose errors.

2 likes 15mo
DS
dr_seongTL3Physician8 May 2025 · edited#3
a.zamora, post #1: On the subject in the title: A pen that felt like it delivered nothing: diagnosing it afterwards Working notes rather than a conclusion. A question about technique rather than about dose. I have been doing the same thing for 14 months and it works, and then I read one of the documentation pages here and realised I may have been… Go to post

post #2 answers the question as asked. The question underneath it is different.

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

9 likes in reply to #1 15mo
RF
ro.friskTL2 Moderator19 May 2025#4

Priming: most pens require priming before the first use (injecting a small amount to fill the needle and line). Not priming can result in no dose being delivered on the first injection.

21 likes 14mo
OO
orbitrap_olaTL3Mass spectrometrist Solution29 May 2025#5

Reusability: some pens are single-use (throw away after one injection). Others can be reused until empty. Confirm which type you have. Reusing a single-use pen is ineffective because the mechanism does not reset.

7 likes 14mo
IA
i.almeidaTL2 Moderator7 Jun 2025#6

I read post #4 twice before replying, because I had assumed the opposite.

Storage after first use: most pens can be stored at room temperature after first use, even if unrefrigerated, for a limited time (often 28 days). Check your specific pen's labelling.

1 like 14mo
PW
PharmNotes_WhitfieldTL4Pharmacist16 Jun 2025#7
f.weiss, post #2: Pen mechanics: most pens are dial-and-inject devices where you dial the dose on the pen and push the button to inject. Understanding your specific pen's mechanism prevents dose errors. Go to post

Needle installation: some pens require a fresh needle for each injection; others have a single needle that stays attached. Check the design of your pen.

5 likes in reply to #2 13mo
NB
n.brobergTL2 Moderator25 Jun 2025#8
dr_seong, post #3: post #2 answers the question as asked. The question underneath it is different. For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use. Go to post

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

15 likes in reply to #3 13mo
BJ
b.jankowiakTL3Regular3 Jul 2025#9
PharmNotes_Whitfield, post #7: Needle installation: some pens require a fresh needle for each injection; others have a single needle that stays attached. Check the design of your pen. Go to post

Picking up post #6: that is the part I would want checked first.

Dose counters: pens show the remaining number of doses. When the counter reaches zero, the pen is empty and cannot deliver more. Noting the counter before injection prevents running out unexpectedly.

30 likes in reply to #7 13mo
IW
i.wojcikTL2 Moderator12 Jul 2025 · edited#10

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

0 likes 13mo
MC
m.coelhoTL2 Moderator20 Jul 2025#11

On post #7 — agreed on the reasoning, with one qualification.

Off-label dosing with a pen: if you want to deliver a dose different from the pen's pre-set steps (e.g., halfway between two step doses), that is off-label use. Some pens allow it; others do not. Confirm before attempting.

4 likes 12mo
BV
b.vestergaardTL2 Moderator28 Jul 2025 · edited#12
i.wojcik, post #10: Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound. Go to post

Injection duration: most pens deliver the dose over several seconds. Holding the button down for the full duration ensures complete delivery. Releasing early can result in underdosing.

0 likes in reply to #10 12mo
HM
h.mbekiTL24 Aug 2025#13
BS
b.solbergTL2 Moderator12 Aug 2025#14

Dose counters: pens show the remaining number of doses. When the counter reaches zero, the pen is empty and cannot deliver more. Noting the counter before injection prevents running out unexpectedly.

12 likes 12mo
CD
cannula_driftTL3Regular19 Aug 2025#15

Worth separating two things that post #11 runs together.

Injection duration: most pens deliver the dose over several seconds. Holding the button down for the full duration ensures complete delivery. Releasing early can result in underdosing.

7 likes 11mo
SV
sa.vogelTL2 Moderator26 Aug 2025#16
m.coelho, post #11: On post #7 — agreed on the reasoning, with one qualification. Off-label dosing with a pen: if you want to deliver a dose different from the pen's pre-set steps (e.g., halfway between two step doses), that is off-label use. Some pens allow it; others do not. Confirm before attempting. Go to post

post #15 is right about the mechanism and I think understates the practical bit.

Off-label dosing with a pen: if you want to deliver a dose different from the pen's pre-set steps (e.g., halfway between two step doses), that is off-label use. Some pens allow it; others do not. Confirm before attempting.

1 like in reply to #11 11mo
B
BGiordanoTL2Member3 Sep 2025#17

Storage after first use: most pens can be stored at room temperature after first use, even if unrefrigerated, for a limited time (often 28 days). Check your specific pen's labelling.

0 likes 11mo
AM
a.mwangiTL2 Moderator10 Sep 2025#18

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

17 likes 11mo
NS
n.silvaTL2 Moderator17 Sep 2025#19

Priming: most pens require priming before the first use (injecting a small amount to fill the needle and line). Not priming can result in no dose being delivered on the first injection.

0 likes 10mo
SL
s.leclercTL4 Moderator24 Sep 2025#20

Reusability: some pens are single-use (throw away after one injection). Others can be reused until empty. Confirm which type you have. Reusing a single-use pen is ineffective because the mechanism does not reset.

0 likes 10mo
FN
f.novakTL2 Moderator1 Oct 2025 · edited#21
orbitrap_ola, post #5: Reusability: some pens are single-use (throw away after one injection). Others can be reused until empty. Confirm which type you have. Reusing a single-use pen is ineffective because the mechanism does not reset. Go to post

post #20 is right about the mechanism and I think understates the practical bit.

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient.

1 like in reply to #5 10mo
K
KTurkingtonTL3Regular7 Oct 2025#22

Needle installation: some pens require a fresh needle for each injection; others have a single needle that stays attached. Check the design of your pen.

7 likes 10mo
SB
s.bergstromTL2 Moderator14 Oct 2025#23

Visibility of the dose: some pens allow you to see the insulin remaining; others do not. Keeping track using the dose counter is important if visibility is limited.

17 likes 9mo
TN
t.ndiayeTL221 Oct 2025#24
AC
a.cardosoTL2 Moderator27 Oct 2025#25

Pen mechanics: most pens are dial-and-inject devices where you dial the dose on the pen and push the button to inject. Understanding your specific pen's mechanism prevents dose errors.

0 likes 9mo
BR
buffer_reviewTL3Regular3 Nov 2025#26

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

3 likes 9mo
AN
a.norgaardTL2 Moderator9 Nov 2025#27

Picking up post #24: that is the part I would want checked first.

Pen confusion between compounds: if you are using multiple pens or alternating pens, confirming you have the correct pen before injection prevents administration errors. Check the label every time.

11 likes 9mo
TI
trough_indexTL3Regular16 Nov 2025#28
a.zamora, post #1: On the subject in the title: A pen that felt like it delivered nothing: diagnosing it afterwards Working notes rather than a conclusion. A question about technique rather than about dose. I have been doing the same thing for 14 months and it works, and then I read one of the documentation pages here and realised I may have been… Go to post

Coming back to post #26, because the follow-up matters more than the original answer.

Pen mechanics: most pens are dial-and-inject devices where you dial the dose on the pen and push the button to inject. Understanding your specific pen's mechanism prevents dose errors.

24 likes in reply to #1 8mo
AK
ak.kravchenkoTL222 Nov 2025#29
AD
ambient_draftTL3Regular28 Nov 2025 · edited#30

Injection duration: most pens deliver the dose over several seconds. Holding the button down for the full duration ensures complete delivery. Releasing early can result in underdosing.

16 likes 8mo