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Devices · Syringes & needles · continued

Reading U-100 graduations, with a conversion table posts 31–42

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

DN
d.ndiayeTL2 Moderator3 Jun 2026#31

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

12 likes 2mo
LA
l.aaltonenTL3Regular8 Jun 2026#32
b.okonkwo, post #16: This follows post #13 rather than contradicting it. Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less. Go to post

Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.

4 likes in reply to #16 2mo
MD
m.dumitruTL2 Moderator13 Jun 2026#33

Coming back to post #31, because the follow-up matters more than the original answer.

Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a source of dosing error.

0 likes 1mo
DW
diluent_watchTL2Member18 Jun 2026#34

Picking up post #31: that is the part I would want checked first.

Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice.

25 likes 1mo
GV
g.verhoevenTL223 Jun 2026#35
Z
ZieglerTL3Regular28 Jun 2026#36
diluent_watch, post #34: Picking up post #31: that is the part I would want checked first. Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice. Go to post

post #35 is right about the mechanism and I think understates the practical bit.

Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers.

7 likes in reply to #34 30d
BN
b.nwosuTL2 Moderator3 Jul 2026#37
s.rasmussen, post #11: Coming back to post #9, because the follow-up matters more than the original answer. Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity. Go to post

I read post #35 twice before replying, because I had assumed the opposite.

Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and milligrams is the most common syringe error.

0 likes in reply to #11 25d
RS
r.scholtenTL2Member8 Jul 2026#38

Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers.

0 likes 20d
NN
n.norgaardTL2 Moderator13 Jul 2026#39

On post #35 — agreed on the reasoning, with one qualification.

Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.

4 likes 15d
MS
m.stephanopoulosTL3Regular17 Jul 2026#40

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient.

0 likes 11d
EP
e.piresTL222 Jul 2026#41
SK
s.kimaniTL2 Moderator27 Jul 2026#42

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

0 likes 1d

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