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Intersection · Analytics × LOD & LOQ

Analytics topics tagged LOD & LOQ

Topics in Analytics carrying the tag LOD & LOQ. Limits of detection and quantitation.

41 topics

TopicParticipantsRepliesViewsActivity
What I would want from a home test that does not exist yet
The question in the title: What I would want from a home test that does not exist yet I will give what I have already checked below so nobody repeats it. Two reports on the same lot, and I would like help…
APNHSTMGI+46 50 8k 6h
Reading a home test result without over-claiming
Reading a home test result without over-claiming — setting out what I have, and where I think it stops being reliable. Collecting what is known about reading a home test result in one place, because it is…
JPMDKOSAZ+124 137 19k 7h
Coming back to: Lateral-flow and colorimetric approaches: the specificity problem
On the subject in the title: Lateral-flow and colorimetric approaches: the specificity problem Working notes rather than a conclusion. Lateral-flow and colorimetric approaches — I have the observation and I…
JFERMBPNIL+77 89 16k 9h
What consumer-accessible tests can and cannot determine — a second dataset
What consumer-accessible tests can and cannot determine — a second dataset I have a specific reason for asking rather than idle curiosity, and the context is below. Posting a small dataset on…
IZBNBPNN+117 131 45k 10h
Cost versus information: making the trade-off explicitly
Cost versus information: making the trade-off explicitly Writing it up because I had to work it out twice and would rather nobody else did. Asking about cost versus information directly, because I have read…
TVSSDDVBS+2 6 12k 11h
A comparison of home results against a laboratory result on the same vial — does this still hold?
A comparison of home results against a laboratory result on the same vial — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Comparison of home…
BKZSCPFYLP+2 6 15k 11h
Reflectance and photometric devices: precision in practice — a second dataset
Reflectance and photometric devices: precision in practice — a second dataset — setting out what I have, and where I think it stops being reliable. Posting a small dataset on Reflectance and photometric…
IGCOHSFAFP+75 82 17k 12h
Revisiting: Spike-and-recover accuracy for a peptide assay
Revisiting: Spike-and-recover accuracy for a peptide assay — setting out what I have, and where I think it stops being reliable. I was wrong about Spike-and-recover accuracy in a thread last spring and I…
SCVKEC 2 6.8k 21h
What I would want from a home test that does not exist yet — what changed since
Asking directly, because I could not find a straight answer: What I would want from a home test that does not exist yet — what changed since Two reports on the same lot, and I would like help deciding whether…
JCPSIBKTL+101 111 1.9k 21h
What a simple presence test is genuinely useful for
What a simple presence test is genuinely useful for — that is the question, and I have not found it answered plainly anywhere I have looked. Trying to work out what would count as evidence on simple presence…
IBNLV 2 58 1d
Revisiting: Can a home kit substitute for a laboratory report? A careful no
Revisiting: Can a home kit substitute for a laboratory report? A careful no — setting out what I have, and where I think it stops being reliable. I would like to disagree carefully with the settled view on…
WPNLVMSLAD+50 56 9.8k 1d
Specificity, linearity, accuracy, precision, range, robustness — with real criteria
Specificity, linearity, accuracy, precision, range, robustness — with real criteria Writing it up because I had to work it out twice and would rather nobody else did. Trying to establish the boundary…
FNISMLAWM+44 48 12k 1d
Validating a method you did not develop
On the subject in the title: Validating a method you did not develop Working notes rather than a conclusion. What changes if the standard account of validating a method is wrong? I ask because I have been…
CRSOSSSVJW+10 14 15k 3mo
Sample handling between despatch and injection
Sample handling between despatch and injection Writing it up because I had to work it out twice and would rather nobody else did. Trying to work out what would count as evidence on sample handling between…
KREHSSNCNA+63 68 2.4k 3mo
Second pass at: Robustness: the parameters worth deliberately varying
On the subject in the title: Second pass at: Robustness: the parameters worth deliberately varying Working notes rather than a conclusion. Something about Robustness does not reconcile and I would like a…
BSFWDSCVOO+61 66 9.5k 3mo
Spike-and-recover accuracy for a peptide assay
Posting this under the heading it deserves: Spike-and-recover accuracy for a peptide assay Everything below is what sits behind that. Asking about spike-and-recover accuracy on behalf of the question I keep…
VSRLMPMOOB+121 126 1.5k 4mo
About the Method validation category
Specificity, linearity, precision, accuracy, robustness, system suitability, and why two labs disagree. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is…
KTVPAKAJV+1 5 468 5mo
Why one laboratory's 98.4% and another's 96.1% may not contradict — one year on
Asking directly, because I could not find a straight answer: Why one laboratory's 98.4% and another's 96.1% may not contradict — one year on Posting the method first, because I know what the first three…
MSFKJBMRCR+10 14 13k 5mo
Can a home kit substitute for a laboratory report? A careful no
Asking directly, because I could not find a straight answer: Can a home kit substitute for a laboratory report? A careful no I would like to disagree carefully with the settled view on home kit substitute,…
WMFKNRVNDO+122 131 1.7k 5mo
Reading a home test result without over-claiming — what changed since
On the subject in the title: Reading a home test result without over-claiming — what changed since Working notes rather than a conclusion. What changes if the standard account of Reading a home test result is…
KDPMHV 2 12k 6mo
Revisiting: Sample handling between despatch and injection
Posting this under the heading it deserves: Revisiting: Sample handling between despatch and injection Everything below is what sits behind that. Reading back through what has been written here about Sample…
DVEAGTEMNG+5 9 1.1k 6mo
Specificity, linearity, accuracy, precision, range, robustness — with real criteria — a second dataset
On the subject in the title: Specificity, linearity, accuracy, precision, range, robustness — with real criteria — a second dataset Working notes rather than a conclusion. Posting a small dataset on…
MSHFDBTDLG+53 58 7.5k 6mo
What a stability-indicating method is and how you demonstrate one
Asking directly, because I could not find a straight answer: What a stability-indicating method is and how you demonstrate one Posting a small dataset on stability-indicating method. It is mine, it is…
EFRJPKISFD 4 57k 6mo
Why one laboratory's 98.4% and another's 96.1% may not contradict
Why one laboratory's 98.4% and another's 96.1% may not contradict I have a specific reason for asking rather than idle curiosity, and the context is below. Posting the method first, because I know what the…
LCMEHMLPFC+28 37 457 7mo
An inter-laboratory comparison on one lot, tabulated — what changed since
An inter-laboratory comparison on one lot, tabulated — what changed since — setting out what I have, and where I think it stops being reliable. What changes if the standard account of inter-laboratory…
IADCKTFHK+24 28 3.3k 7mo
LOD and LOQ: definitions people get wrong
LOD and LOQ: definitions people get wrong — setting out what I have, and where I think it stops being reliable. What changes if the standard account of LOD and LOQ is wrong? I ask because I have been treating…
EISFCN 2 43k 8mo
Coming back to: Why quantitation is the hard part, not detection
Why quantitation is the hard part, not detection — that is the question, and I have not found it answered plainly anywhere I have looked. Collecting what is known about quantitation in one place, because it…
SCNGDBFE+86 92 54k 8mo
Lateral-flow and colorimetric approaches: the specificity problem
Lateral-flow and colorimetric approaches: the specificity problem — setting out what I have, and where I think it stops being reliable. Lateral-flow and colorimetric approaches, and specifically the version…
DHVKVS 2 4k 9mo
An inter-laboratory comparison on one lot, tabulated
On the subject in the title: An inter-laboratory comparison on one lot, tabulated Working notes rather than a conclusion. Collecting what is known about inter-laboratory comparison in one place, because it is…
ZAMGCRKB 3 17k 10mo
Second pass at: LOD and LOQ: definitions people get wrong
Posting this under the heading it deserves: Second pass at: LOD and LOQ: definitions people get wrong Everything below is what sits behind that. Something about LOD and LOQ does not reconcile and I would like…
SPNIBIMG+47 51 40k 10mo