Tags · Evidence
heterogeneity
Variation in effect across studies or subgroups.
Related in this group: STEP programme · SURMOUNT programme · SURPASS programme · SELECT trial · FLOW trial · SOUL trial · TRIUMPH programme · PIONEER programme · SUSTAIN programme · LEADER trial · randomised trial · meta-analysis
35 topics · page 1 of 2
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When a network meta-analysis is defensible and when it is not
When a network meta-analysis is defensible and when it is not I have a specific reason for asking rather than idle curiosity, and the context is below. Network meta-analysis, from the point of view of someone…
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2 | 27k | 4h | |
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[2026 update] Correlation in a self-tracked dataset: what it can support
Posting this under the heading it deserves: Correlation in a self-tracked dataset: what it can support Everything below is what sits behind that. Posting a small dataset on Correlation. It is mine, it is…
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2 | 31k | 6h | |
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Revisiting: What pooling buys you and what it destroys
On the subject in the title: Revisiting: What pooling buys you and what it destroys Working notes rather than a conclusion. Pooling buys — I have the observation and I do not trust my interpretation of it, so…
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+97 | 107 | 4k | 19h |
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Risk-of-bias tools and the judgement they conceal — does this still hold?
Risk-of-bias tools and the judgement they conceal — does this still hold? — that is the question, and I have not found it answered plainly anywhere I have looked. Asking about Risk-of-bias tools on behalf of…
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+26 | 30 | 5.8k | 23h |
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Publication bias detection and its low power
On the subject in the title: Publication bias detection and its low power Working notes rather than a conclusion. Working notes on publication bias detection rather than a conclusion. I would rather post the…
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2 | 3.2k | 1d | |
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Sample size intuition for a personal experiment — does this still hold?
Sample size intuition for a personal experiment — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Reading back through what has been written…
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+33 | 38 | 26k | 23d |
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What a confidence interval means, from scratch
What a confidence interval means, from scratch — that is the question, and I have not found it answered plainly anywhere I have looked. Asking about confidence interval directly, because I have read four…
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2 | 2.6k | 2mo | |
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Measurement error in home scales, with a worked standard deviation — the long version
On the subject in the title: Measurement error in home scales, with a worked standard deviation — the long version Working notes rather than a conclusion. A narrow question about Measurement error in home…
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+96 | 105 | 2k | 2mo |
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Publication bias detection and its low power — does this still hold?
The question in the title: Publication bias detection and its low power — does this still hold? I will give what I have already checked below so nobody repeats it. Collecting what is known about Publication…
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+24 | 28 | 2.4k | 3mo |
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Second pass at: What pooling buys you and what it destroys
Posting this under the heading it deserves: Second pass at: What pooling buys you and what it destroys Everything below is what sits behind that. Something about pooling buys does not reconcile and I would…
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+32 | 36 | 19k | 4mo |
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Prediction intervals and why they are more honest than confidence intervals
Posting this under the heading it deserves: Prediction intervals and why they are more honest than confidence intervals Everything below is what sits behind that. I have spent a fortnight trying to pin…
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+21 | 25 | 46k | 4mo |
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Measurement error in home scales, with a worked standard deviation
Measurement error in home scales, with a worked standard deviation Writing it up because I had to work it out twice and would rather nobody else did. What changes if the standard account of measurement error…
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+26 | 31 | 4.3k | 4mo |
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Heterogeneity as information rather than as a nuisance
Posting this under the heading it deserves: Heterogeneity as information rather than as a nuisance Everything below is what sits behind that. An honest uncertainty about heterogeneity rather than a disguised…
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+88 | 95 | 1.2k | 6mo |
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Measurement error in home scales, with a worked standard deviation — a second dataset
Measurement error in home scales, with a worked standard deviation — a second dataset — setting out what I have, and where I think it stops being reliable. Posting a small dataset on Measurement error in home…
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2 | 13k | 7mo | |
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About the Statistics category
Effect sizes, intervals, multiplicity, and the difference between absent and undetected. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its…
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+4 | 8 | 2.3k | 7mo |
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Pooling trials with different estimands — what changed since
Pooling trials with different estimands — what changed since — setting out what I have, and where I think it stops being reliable. What changes if the standard account of Pooling trials with different…
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+57 | 64 | 12k | 7mo |
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What pooling buys you and what it destroys
The question in the title: What pooling buys you and what it destroys I will give what I have already checked below so nobody repeats it. The question about pooling buys that I actually want answered is the…
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+74 | 83 | 6.6k | 8mo |
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What a confidence interval means, from scratch — the long version
The question in the title: What a confidence interval means, from scratch — the long version I will give what I have already checked below so nobody repeats it. Asking about confidence interval directly,…
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+16 | 20 | 2.3k | 8mo |
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Risk-of-bias tools and the judgement they conceal
Risk-of-bias tools and the judgement they conceal Writing it up because I had to work it out twice and would rather nobody else did. I have spent a fortnight trying to pin risk-of-bias tools down and I want…
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+8 | 12 | 21k | 11mo |
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Multiplicity when you track fifteen variables
Multiplicity when you track fifteen variables — setting out what I have, and where I think it stops being reliable. Asking about multiplicity directly, because I have read four threads on it and each answered…
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2 | 60k | 11mo | |
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[2026 update] Heterogeneity as information rather than as a nuisance
Heterogeneity as information rather than as a nuisance Writing it up because I had to work it out twice and would rather nobody else did. I have seen SURPASS-4 ( Lancet , 2021) cited in support of a claim I…
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4 | 32k | 11mo | |
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Regression to the mean in progress reports
On the subject in the title: Regression to the mean in progress reports Working notes rather than a conclusion. Something about regression does not reconcile and I would like a second pair of eyes before I…
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+30 | 34 | 49k | 12mo |
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Random versus fixed effects: choosing rather than defaulting
Random versus fixed effects: choosing rather than defaulting — setting out what I have, and where I think it stops being reliable. Random versus fixed effects, and specifically the version of it that the…
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+16 | 20 | 22k | 13mo |
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About the Meta-analyses category
Pooled estimates, heterogeneity, publication bias, and when pooling was a mistake. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its author…
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4 | 15k | 13mo | |
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Individual participant data versus aggregate data
Posting this under the heading it deserves: Individual participant data versus aggregate data Everything below is what sits behind that. Something about individual participant data versus aggregate does not…
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+30 | 34 | 64k | 14mo |
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Second pass at: Regression to the mean in progress reports
Second pass at: Regression to the mean in progress reports Writing it up because I had to work it out twice and would rather nobody else did. Posting a small dataset on Regression. It is mine, it is…
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+71 | 75 | 4k | 17mo |
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Coming back to: Reading a meta-analysis you disagree with, fairly
Reading a meta-analysis you disagree with, fairly Writing it up because I had to work it out twice and would rather nobody else did. Reading a meta-analysis — I have the observation and I do not trust my…
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+30 | 34 | 9.3k | 17mo |
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Random versus fixed effects: choosing rather than defaulting — a second dataset
On the subject in the title: Random versus fixed effects: choosing rather than defaulting — a second dataset Working notes rather than a conclusion. Posting a small dataset on Random versus fixed effects. It…
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+95 | 106 | 20k | 17mo |
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Second pass at: Multiplicity when you track fifteen variables
Posting this under the heading it deserves: Second pass at: Multiplicity when you track fifteen variables Everything below is what sits behind that. Two things I would like separated before anyone answers on…
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2 | 12k | 18mo | |
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Sample size intuition for a personal experiment
On the subject in the title: Sample size intuition for a personal experiment Working notes rather than a conclusion. A follow-up question about sample size intuition that I did not know to ask the first time.…
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4 | 62k | 18mo |