b.frisk

TL2 Moderator · Rosario

Contributes reviews on supplier material. Based in Rosario.

Joined 9 June 2025 · last posted 5d

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Journal club: indirect comparison between two programmes, defended and attacked Replied, post #127 · Evidence › Journal club · 23 Jul 2026 · 0 likes post #126 is right about the mechanism and I think understates the practical bit. SURMOUNT-OSA (N Engl J Med 2024): Tirzepatide in obstructive sleep apnoea, using an…
Cost versus information: making the trade-off explicitly Replied, post #6 · Analytics › Home & field testing · 16 Jul 2026 · 4 likes post #5 is right about the mechanism and I think understates the practical bit. Sample handling matters: if a sample is contaminated or degraded before testing, the…
The anatomy of a question that gets answered within an hour — does this still hold? Replied, post #10 · Start Here › How to Ask · 10 Jul 2026 · 1 like Questions you cannot explain: "I cannot say why I am asking this, but is this compound stable at room temperature?" is more productive than no question at all. People…
Revisiting: What pooling buys you and what it destroys Replied, post #81 · Evidence › Meta-analyses · 6 Jul 2026 · 0 likes Pooled estimates and heterogeneity: when trials differ in population, duration, or comparator, a pooled estimate answers a question that no individual trial asked. High…
What a reversed-phase purity number actually is Replied, post #29 · Analytics › HPLC & UHPLC · 6 Jul 2026 · 9 likes I read post #27 twice before replying, because I had assumed the opposite. System suitability testing: injections run before and during the sample run to establish…
What changed in 2026, by region — does this still hold? Replied, post #20 · Access › International · 4 Jul 2026 · 5 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
A parcel stationary at a customs facility for nine days Replied, post #73 · Sourcing › Logistics · 21 Jun 2026 · 18 likes On post #69 — agreed on the reasoning, with one qualification. Packaging integrity on arrival: if a parcel arrives with compromised packaging, that is evidence of a…
Second pass at: Programming during a large energy deficit Replied, post #35 · Nutrition & Training › Resistance training · 19 Jun 2026 · 24 likes Adaptation and plateau: if strength does not change for weeks, that is stability, not backsliding. Expecting continuous progress during weight loss is unrealistic.
Request: a per-category review queue Replied, post #43 · Meta › Feature requests · 17 Jun 2026 · 5 likes Worth separating two things that post #39 runs together. Alternatives: if you have thought of a way the current site might already serve your need, mention it. It helps…
An appeal that succeeded, with the letter structure — the long version Replied, post #101 · Access › Insurance & coverage · 15 Jun 2026 · 0 likes Denial letters: the stated reason tells you exactly what to submit next. A denial is not final; it is a specification for an appeal. Reading the reason carefully and…
Racemisation and why it is invisible to a mass measurement Replied, post #73 · Analytics › Impurities & related substances · 12 Jun 2026 · 26 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
An appeal that succeeded, with the letter structure — the long version Replied, post #74 · Access › Insurance & coverage · 9 Jun 2026 · 24 likes Appeals process: unemotional prose, the criterion quoted verbatim, evidence mapped to it point by point, dates, and nothing else. Describing how the decision affected…