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Devices · Syringes & needles · continued

A ten-fold dose error caught before injection — one year on posts 61–90

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

LA
l.aaltonenTL3Regular2 Aug 2025 · edited#61
a.vestergaard, post #59: Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers. Go to post

post #60 is right about the mechanism and I think understates the practical bit.

Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and milligrams is the most common syringe error.

5 likes in reply to #59 12mo
SM
so.mbekiTL2 Moderator2 Aug 2025#62
m.dalgaard, post #12: I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient. Go to post

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

13 likes in reply to #12 12mo
W
WickramasingheTL2Member3 Aug 2025#63

Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose.

27 likes 12mo
WM
w.moreauTL2 Moderator3 Aug 2025#64

I read post #62 twice before replying, because I had assumed the opposite.

Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.

0 likes 12mo
N
NLoughranTL3Regular3 Aug 2025#65
ambient_review, post #5: Picking up post #2: that is the part I would want checked first. Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice. Go to post

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

2 likes in reply to #5 12mo
KK
k.karlsenTL2 Moderator3 Aug 2025#66

Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.

9 likes 12mo
HN
h.nicolaidesTL3Regular3 Aug 2025#67

Picking up post #64: that is the part I would want checked first.

Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.

20 likes 12mo
PO
p.onwukaTL2 Moderator3 Aug 2025#68

Coming back to post #66, because the follow-up matters more than the original answer.

Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a source of dosing error.

0 likes 12mo
MS
m.stephanopoulosTL3Regular3 Aug 2025#69
Buchholz, post #52: post #51 answers the question as asked. The question underneath it is different. Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers. Go to post

Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice.

0 likes in reply to #52 12mo
ZI
z.iyerTL2 Moderator3 Aug 2025 · edited#70

Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers.

5 likes 12mo
FF
f.fonsecaTL2 Moderator3 Aug 2025#71

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

2 likes 12mo
FW
f.wojcikTL2 Moderator3 Aug 2025#72
s.teixeira, post #19: Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity. Go to post

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

0 likes in reply to #19 12mo
SR
s.rasmussenTL2 Moderator3 Aug 2025#73

On post #69 — agreed on the reasoning, with one qualification.

Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.

26 likes 12mo
VB
v.bhattacharyaTL2 Moderator3 Aug 2025#74

post #73 answers the question as asked. The question underneath it is different.

Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.

12 likes 12mo
SD
s.duarteTL2 Moderator3 Aug 2025#75

Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose.

0 likes 12mo
AS
a.sorensenTL2 Moderator3 Aug 2025#76
e.mbeki, post #28: Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive. Go to post

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

0 likes in reply to #28 12mo
AS
a.salcedoTL3Regular3 Aug 2025#77

Worth separating two things that post #73 runs together.

Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and milligrams is the most common syringe error.

19 likes 12mo
NN
n.nakamuraTL2 Moderator3 Aug 2025#78

Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice.

8 likes 12mo
NV
n.villalobosTL2 Moderator3 Aug 2025#79
m.vukovic, post #22: On post #18 — agreed on the reasoning, with one qualification. Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses. Go to post

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

0 likes in reply to #22 12mo
BI
blank_injectionTL2Analytical chemist3 Aug 2025#80
ambient_review, post #5: Picking up post #2: that is the part I would want checked first. Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice. Go to post

Picking up post #77: that is the part I would want checked first.

Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.

27 likes in reply to #5 12mo
GV
g.verhoevenTL2 Moderator3 Aug 2025#81
s.bruun, post #29: Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose. Go to post

This follows post #78 rather than contradicting it.

Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.

9 likes in reply to #29 12mo
RS
r.scholtenTL2Member3 Aug 2025#82
cannula_trace, post #48: Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and milligrams is the most common syringe error. Go to post

I read post #80 twice before replying, because I had assumed the opposite.

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

20 likes in reply to #48 12mo
ON
o.nybergTL2 Moderator3 Aug 2025#83

Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose.

0 likes 12mo
Z
ZieglerTL3Regular3 Aug 2025#84

Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.

2 likes 12mo
ZV
z.vogelTL2 Moderator3 Aug 2025#85
n.nakamura, post #78: Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice. Go to post

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient.

14 likes in reply to #78 12mo
DW
diluent_watchTL2Member3 Aug 2025#86

Coming back to post #84, because the follow-up matters more than the original answer.

Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers.

28 likes 12mo
CV
ca.vermeulenTL2 Moderator3 Aug 2025#87

post #86 answers the question as asked. The question underneath it is different.

Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a source of dosing error.

0 likes 12mo
W
WoodhouseTL2Member3 Aug 2025 · edited#88

Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and milligrams is the most common syringe error.

5 likes 12mo
RD
r.danquahTL2 Moderator3 Aug 2025#89
f.espinoza, post #51: On post #47 — agreed on the reasoning, with one qualification. Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose. Go to post

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

19 likes in reply to #51 12mo
KF
k.fonsecaTL2 Moderator3 Aug 2025#90

Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.

0 likes 12mo