post #7 answers the question as asked. The question underneath it is different.
I disagree with the reply above, and I think the disagreement is substantive rather than terminological.
The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient.
Worth separating two things that post #19 runs together.
Temperature excursions: brief excursions above 8 °C are tolerable for most compounds. Hours to a day at room temperature is usually acceptable. Days to weeks at room temperature risks degradation.
Shipping container and cold packs: reputable suppliers use insulated containers with cold packs designed to arrive cool. Checking on arrival that cold packs are still cold is a sign the chain was maintained.
Coming back to post #50, because the follow-up matters more than the original answer.
Freeze-thaw: some peptides tolerate freezing; others do not. Check your compound's labelling. Generally, repeated freeze-thaw is worse than single freeze-thaw.
Travel with medication: carrying a vial across borders requires planning if temperatures will exceed the range or if journey time is long. Insulated travel cases with ice packs are common solutions.
Shipment during summer or to hot climates: consider shipping to a cold-storage facility rather than to home if temperatures will be high. Alternatively, time shipment to arrive when you can refrigerate immediately.
I read post #126 twice before replying, because I had assumed the opposite.
Assessing an excursion: if a package sat at room temperature for a time, visual inspection (cloudiness, discoloration, particles) can alert you to problems. Not visible does not mean not damaged, but visible problems are a reason to contact the supplier.
Temperature excursions: brief excursions above 8 °C are tolerable for most compounds. Hours to a day at room temperature is usually acceptable. Days to weeks at room temperature risks degradation.
Read the full topic (156 posts)
| Topic | Participants | Replies | Views | Activity |
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About the Cold chain category
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